2023-04-27 17:25:34
Dhe development has not yet been evaluated by independent experts in a peer review process, but the journal Nature has already pointed out the possible “democratization of microscopy” in an informative article. What is meant is a new, cost-effective method for making tiny structures visible, which outshines any resolution previously achieved in light microscopy, and which also works with any light microscope, even an outdated one. This should now also enable scientists to resolve objects in the nanometer range that cannot afford large-scale devices costing millions of euros.
We are talking about the so-called ONE microscopy. It was developed by Silvio Rizzoli and Ali Shaib from the University Medical Center Göttingen and other colleagues. ONE actually stands for the number one, because Rizzoli and Shaib can achieve a resolution of one nanometer or less with this form of microscopy. Commercial high-performance light microscopes resolve distances between 40 and 70 nanometers, conventional light microscopes at most 200 nanometers due to the wave nature of light. Objects that are closer together than the resolution limit of the respective microscope allows can no longer be perceived separately, but only as a blurred spot.
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