2023-05-16 03:30:11
Immunocompromised patients, such as HIV-positive people, often require special therapy. But what happens if they contract the monkeypox virus? Researchers are now examining the effectiveness of Tecovirimat in HIV-infected people.
Tecovirimat is a Virostatikumused to treat severe Mpox-Symptoms is allowed. The drug was originally used to treat relatives Pockenvirus developed and approved. However, its effectiveness has not yet been adequately studied in people with monkeypox. Doctors therefore feared that HIV-positive People with Mpox would respond less well to tecovirimate than HIV-negative people.
Painless and tolerable
“Our study suggests that patients with well-controlled HIV responded to treatment with Tecovirimat in a similar way to people without HIV,” says infectiologist Dr. Jason Sugar. In one study, Zucker and his team analyzed data from 154 patients who tested positive for Mpox and were treated with tecovirimat. 72 of those treated were HIV positive.
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The result: Almost all patients were pain-free at the end of the treatment, regardless of their HIV status. The drug was equally well tolerated by both patient groups. Although further studies are needed to prove the drug’s effectiveness against Mpox, the study first confirms the good tolerability of tecovirimat.
Poor HIV management
There is evidence that people with strong weakened immune system – including people with poorly controlled HIV infection – are at higher risk of serious illness and death from Mpox. In the study, only four people had low CD4 values — a sign of poorly controlled HIV infection — so the researchers were unable to compare treatment outcomes in this group.
prevent further outbreaks
“There are major disparities in access to care and treatment for people living with HIV, which contributes to inequalities in Mpox diagnosis and treatment and affects outcomes,” Zucker said. He adds that the Mpox epidemic has virtually stopped in the United States, while cases are rising in other countries. “We could see another outbreak of Mpox if we don’t ensure that everyone at risk is vaccinated,” said the infectious disease specialist.
Note d. Red.: The WHO now has the status of an international health emergency for Mpox raised up.
This text is based on a press release des Columbia University Irving Medical Center. Here you can find the original publication.
Image source: Dolo Iglesias, unsplash.
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