The gene-edited bacteria that is the last great hope in the fight against cancer

by time news

2023-05-21 08:55:57

A study developed by researchers in China and published in the journal Cell Reports Medicine has revealed a finding that could become a revolution for medicine and the fight against cancer.

As collected Gizmodothe finding consists of the development of two onion from E. coli bacteria genetically designed to combat different types of tumors in mice.

The authors of the study, belonging to the Faculty of Medicine of the shenzhen universityit’s about bacteria doing all the ‘dirty work’ in fighting cancer disease.

First of all, the strain called mp105 it is designed to attack a variety of different types of cancer and can be administered intravenously. But the key is that this strain survives for a very short time, which would limit its potential to harm non-cancerous cells.

In addition, there is the strain m6001, designed to live longer and search for solid tumors by detecting and moving away from glucose (tumors that tend to lack glucose). This bacterium is administered directly to the tumor site without safety concerns.

In laboratory tests, mp105 completely killed cancer cells, depleted tumor-associated macrophages, a group of immune cells found in tumors that are thought to help them survive, and seemed stimulate the body’s natural immune response to cancer.

For its part, M6001 showed an anticancer activity even more potent against the solid tumors against which it was deployed, although it showed better results when both strains were used together.

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