2023-05-24 11:43:20
How does etoricoxib work?
Etoricoxib acts as a selective inhibitor of the enzyme cyclooxygenase-2 (COX-2). COX-2 is an enzyme involved in the production of pro-inflammatory prostaglandins. Prostaglandins contribute to the development of inflammation, pain and fever.
By inhibiting COX-2, etoricoxib reduces the production of these pro-inflammatory prostaglandins. This will make the Inflammatory response in the body is reduced and pain and inflammation can be reduced.
Unlike non-selective NSAIDs, which inhibit both COX-2 and COX-1, etoricoxib selectively targets COX-2. COX-1 is an enzyme that plays an important role in protecting the gastrointestinal lining and maintaining normal blood clotting. By selectively inhibiting COX-2, etoricoxib attempts to reduce the risk of gastrointestinal bleeding and ulcers that can be associated with the use of other NSAIDs.
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