Severe obesity of genetic origin weakens children’s immunity

by time news

2023-10-08 18:06:40

“Children who suffer from obesity before the age of 6 are those who have the strongest genetic predisposition,” indicates Professor Béatrice Dubern, specialist in childhood obesity in the pediatric nutrition and gastroenterology department at Trousseau hospital, at Paris (AP-HP). New Africa – stock.adobe.com

DECRYPTION – Mutations in certain genes appear to increase vulnerability to infections.

Obesity is increasingly common in Western countries, but it was in Pakistan that researchers from the European Diabetes Genomics Institute (Egid) worked to learn more about the impact of genetic forms of obesity. obesity. “Populations in which there is still strong inbreeding make it possible to obtain unparalleled genetic data, explains Professor Froguel, director of the Egid institute, who led this research. Genetic anomalies are more frequent there, as are so-called homozygous people, that is to say people whose two copies of certain genes are mutated. This research, which was the subject of two recent publications, made it possible, on the one hand, to identify a new gene involved in severe obesity and, on the other hand, to highlight the impact of certain mutations on health. of these children.

The long-term health risks posed by obesity are well identified. This chronic disease is, among other things, known to increase…

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