2023-10-08 19:18:14
Title: New Dementia Drug Shows Promise in Slowing Memory Loss
Publication: HomeWorld
Date: October 8, 2023
Author: Michelle Mantey
A new drug called Leqembi offers hope to patients in the early stages of dementia by targeting the root cause of memory loss. Developed by the Japanese pharmaceutical company Eisai and the American pharmaceutical company Biogen, the drug contains the active ingredient lecanemab and is administered through an infusion.
According to scientific studies conducted in the United States and approved by the American Food and Drug Administration (FDA) on July 6, 2023, Leqembi shows promise in slowing down the progression of dementia. Unlike other dementia drugs that stimulate brain performance, lecanemab targets protein deposits in the brain, which interfere with the transmission of information and ultimately lead to the death of nerve cells. By targeting these proteins, the drug aims to slow down the deposits.
The effects of Leqembi were evaluated in a phase 3 study involving 1,795 participants. The study showed that the progression of the disease was delayed by 27 percent. Specifically, the medication was found to slow memory loss by five months. In contrast, the placebo group did not exhibit any significant changes.
FDA Neurology Drugs Director Teresa Buracchio stated, “This confirmatory study demonstrated that it is a safe and effective treatment for patients with Alzheimer’s disease.” However, it is important to note that brain swelling occurred in 17 percent of the test subjects. While three deaths were recorded, it is believed that none were directly caused by the drug.
Despite these potential side effects, the promising results have led to the drug’s approval in the United States. The manufacturer has also submitted an application for approval to the European Medicines Agency (EMA), indicating a potential expansion of its availability.
It is worth mentioning that dementia and Alzheimer’s disease can affect individuals under the age of 65 as well. The German Alzheimer Society suggests that the number of affected individuals may be higher than currently reported.
While Leqembi offers hope for dementia patients, it is essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment. The use of medication or nutritional supplements should always be discussed with a doctor beforehand.
As research in the field of dementia continues to progress, pharmaceutical companies and scientists strive to develop effective and safe treatments to combat this widespread illness.]
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