2023-11-14 12:38:54
A study carried out by the Complutense University of Madrid (UCM) that is part of the GESNO-COVID multi-institutional project –led by the Gregorio Marañón General University Hospital– has demonstrated the transplacental transfer of antibodies in 86.3% of newborns of mothers who had undergone covid-19 during pregnancy.
The study, published in BMC Pregnancy and Childbirthwas carried out with 51 mother-child pairs, including births from April 2020 to March 2021. By then, no mother had been vaccinated against SARS-COV-2, so the antibodies andThey are the result of contracting the disease during pregnancy. In turn, no child has been diagnosed with Covid during the course of the study, ensuring that the antibodies came from the maternal placenta.
The study demonstrates the impact that the maternal production of antibodies against covid has to protect the newborn through the passage of these. “If the woman has antibodies in a safer way through vaccination, these will be transferred to the newborn and he will therefore be protected against infection,” he highlights. Maria Luisa Navarroresearcher in the Department of Public and Maternal-Child Health of the UCM.
If the woman has antibodies more safely through vaccination, these will be transferred to the newborn and he will therefore be protected against infection.
María Luisa Navarro, researcher at the UCM
Later work carried out on the infant protection Vaccinating the pregnant woman against Covid and the safety of this strategy have meant that today the pregnant woman is considered a subsidiary of receiving the vaccine, obtaining double protection, hers and that of the newborn.
Loss of antibodies
In the study, it was observed that the amount of antibodies that the babies had at the time of birth was related to the amount of antibodies that the mother had. As time passes, these decrease, and two months after delivery, 66.7% of infants had positive serology, while at six months only 13.7%.
On the other hand, this protective effect has not been observed in newborns of mothers with acute infection at the time of delivery. These children did not present antibodies, since they had not yet developed in their mothers.
Given the severity of COVID in pregnant women, it is necessary for pregnant women to be vaccinated against SARS-CoV-2, just as they are vaccinated against other diseases such as flu and whooping cough.
Maria Luisa Navarro
The GESNEO-COVID project, which has had the help of the “Covid Funds” of the Carlos III Health Institute, is led by the Gregorio Marañón Hospital and centers with maternity wards throughout the national territory have participated. This project consisted of evaluating the impact that infection with the SARS-CoV-2 virus had on pregnant women and newborns.
“Thus, different studies were carried out, where it was possible to demonstrate that pregnant women are a vulnerable population group for SARS-CoV-2 and that perinatal transmission of this virus to the newborn is exceptional. Given the severity of Covid in pregnant women, it is necessary for pregnant women to be vaccinated against SARS-CoV-2, just as they are vaccinated against other diseases such as flu and whooping cough. In the case of SARS-CoV-2 infection, the maternal immunization It will in turn protect your newborn during the first months of life,” concludes Navarro, principal investigator of the project.
Reference:
Vigil-Vázquez, S., Manzanares, Á., Hernanz-Lobo, A. et al. Serologic evolution and follow-up to IgG antibodies of infants born to mothers with gestational COVID. BMC Pregnancy Childbirth.
Fuente:
Complutense University of Madrid
Rights: Creative Commons.
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