The Impact of Cannabis on the Human Epigenome: Study of Over 1,000 Adults

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New Study Suggests Cannabis Use Can Cause Changes in Human Body’s Epigenome

A new study has suggested that the use of cannabis may cause changes in the human body’s epigenome, which can affect how our genes are activated or deactivated, ultimately changing how our bodies function. The study, conducted by a team of researchers from Northwestern University Feinberg School of Medicine, found associations between cannabis use and multiple epigenetic markers in over 1,000 adults.

The study, published in Molecular Psychiatry, involved analyzing blood samples from participants over a 20-year period, during which they were asked about their cannabis use. The researchers observed changes in DNA methylation levels, a key epigenetic modification, in individuals who had used cannabis recently or over a long period of time.

According to Lifang Hou, a preventative medical doctor and epidemiologist from Northwestern University, the study identified numerous DNA methylation markers associated with both recent and cumulative cannabis use in the participants’ blood samples. The researchers also found a potential shared epigenetic regulation between tobacco and marijuana use, suggesting a possible overlap in how these substances affect the body’s epigenome.

While the study provides valuable insights into the potential effects of cannabis on the human body, it’s important to note that the findings do not prove that cannabis directly causes these changes or health problems. “Additional studies are needed to determine whether these associations are consistently observed in different populations,” said Drew Nannini, an epidemiologist from Northwestern University.

The researchers hope that further studies will shed light on the long-term effects of cannabis use on health outcomes, particularly in relation to aging-related health issues. With the increasing legalization of cannabis in various regions, understanding its potential impact on the human body’s epigenome and overall health is crucial for making informed decisions about its use.

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