2024-02-16 20:46:36
He Parkinson It is a disease that causes damage to brain cells. However, a promising nanocrystal treatment could change the course of this disorder that affects the nervous system, since it could reverse neurological deficit.
How does gold nanocrystal treatment help brain function?
Phase two clinical trials, where gold nanocrystals administered orally to treat multiple sclerosis (MS) and the Parkinson’s disease, showed favorable advances by significantly reversing metabolites related to energy activity in the brain.
Our brain depends on a continuous supply of energy in the form of adenosine triphosphate (ATP). It is essential for the proper functioning of nerve cells, their communication and the regulation of body functions.
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Some neurodegenerative conditionssuch as MS, Parkinson’s and lateral sclerosis, reduce brain energy rapidly and, in their most severe form, cause a cognitive impairment, loss of motor control and a series of symptoms that affect people’s quality of life.
Researchers discovered that at reverse energy deficit A slower decline or even partial recovery is achieved in patients with neurodegenerative diseases, discovery published for him Journal of Nanobiotechnology.
This study suggests that a treatment with gold nanocrystals It acts as a catalyst, positively altering the energy balance of brain cells, which has been tested in cellular and animal models in previous research.
How was the gold nanocrystal treatment study carried out?
To carry out the research, the scientists recruited 11 patients with relapsing MS and 13 with Parkinson in two phase two clinical trials called REPAIR-MS and REPAIR-PD.
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Participants received baseline brain magnetic resonance (MR) spectroscopy to determine the relationship of brain energy with the levels of other molecules associated with cellular energy metabolism. After treatment with gold nanocrystals over 12 weeks, there was an increase in brain energy.
On the other hand, energy molecules, including ATP, normalized, showing an improvement in the functional symptoms of both diseases.
What are the side effects of gold nanocrystal treatment?
To date, none of the patients showed serious adverse side effects related to the gold nanocrystal treatment.
While the results are encouraging, additional studies are needed to show that this treatment could change the lives of millions of people who suffer from neurodegenerative conditionsalthough it is already a promising advance.
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