2024-06-05 05:49:21
Participated in ‘2024 BioUSA’ in San Diego, USA
Proposal of high-concentration drug optimization CDO resolution
Common inoculated cell focus 30 instances greater
Personalized CDO service bundle ‘Choose Tailor’ rebranding
116 cumulative CDO contracts over 6 years… ADC improvement contract this 12 months
Vice President Min Ho-seong “CDO competitiveness will increase by way of platform improvement and repair enlargement”
Samsung BioLogics launched a brand new contract improvement group (CDO) platform that helps the event of high-concentration biopharmaceuticals. The aim is to strengthen CDO competitiveness by way of a ‘customer-tailored’ technique.
Samsung BioLogics unveiled its new CDO platform ‘S-Tensify’ on the ‘2024 Bio Worldwide Conference (BioUSA)’, the world’s largest pharmaceutical and bio exhibition held in San Diego, USA on the third (native time). .
S-Tensify is a platform for growing high-concentration biopharmaceuticals by making use of cutting-edge tradition know-how. It was launched as a platform utilized to CDO by increasing the scope of the ‘N-1 Perfusion’ know-how utilized to consignment manufacturing (CMO) in 2019.
In line with Samsung BioLogics, the And Minus One Perfusion know-how utilized to S-Tensify can improve the inoculation cell density within the stage simply earlier than last cell tradition (N-1) by a median of 30 instances. It’s mentioned that by way of this, productiveness may be vastly elevated when inoculating within the last cell tradition stage (N). N Minus One Perfusion is a know-how that cultivates high-concentration cells by present process perfusion tradition within the N-1 stage and concurrently performing cell tradition and waste elimination.
Samsung BioLogics defined that primarily based on this know-how, it has overcome the constraints of current strategies, which had been unable to considerably improve cell focus as a result of waste accrued within the incubator.
A Samsung BioLogics official mentioned, “By way of S-Tensify, we’ve got expanded our capabilities from the normal fed tradition technique (Fed Batch) to a high-concentration tradition technique with improved productiveness and count on to have the ability to present enhanced CDO companies.” “I do it,” he mentioned.
On today, Samsung BioLogics additionally launched the rebranded CDO service ‘SelecTailor’ together with the brand new platform. Choose Tailor is a service that gives personalized CMC (Chemistry, Manufacturing, Management) packages optimized primarily based on the shopper’s distinctive materials traits and improvement technique. They seem like extra actively advertising their CDO by making use of their model to the ‘Personalized CMC Resolution’ launched in August final 12 months.
A Samsung BioLogics official mentioned, “With the emergence of latest kinds of therapies and the activation of regulatory companies’ fast assessment programs, establishing a sophisticated improvement technique is changing into extra vital.” He added, “Samsung BioLogics optimizes the properties of supplies owned or secured by prospects by way of Choose Tailor. “We offer personalized companies and suggest improvement methods to assist our prospects’ profitable new drug improvement,” he defined.
Samsung Biologics, which began the CDO enterprise in 2018 and has supplied one-stop options from cell line improvement to scientific trial (IND) software and commercialization manufacturing phases, plans to proceed to develop associated platforms and broaden service areas to strengthen CDO competitiveness. .
Final 12 months, we carried out in-depth evaluation and management of ‘S-CHOsient’, our personal short-term expression platform that helps the creation of early candidate supplies for biopharmaceuticals, and N-Glycan, a key high quality attribute of the fabric. Launched ‘S-Glyn’, a platform that helps materials improvement. Previous to this, in 2022, the bispecific antibody improvement platform ‘S-Twin’ and the self-development feasibility analysis platform ‘Developick’ had been launched.
Efficiency is constant steadily due to the launch of differentiated platform applied sciences and companies. As of the primary quarter of final 12 months, the entire variety of contracts for Samsung BioLogics’ CDO mission was 116. Particularly, in February of this 12 months, a CDO contract was signed with home bio firm RigaChem Bioscience to develop antibody-drug conjugate (ADC), which is taken into account a next-generation anticancer drug. It’s evaluated that it has confirmed that it’s attainable to offer optimized CDO companies even within the space of next-generation therapy improvement.
Ho-seong Min, Vice President and Head of CDO Growth Middle at Samsung Biologics, mentioned, “We are able to count on fast market entry whereas decreasing the chance of biopharmaceutical improvement by offering the tradition technique and customised service desired by our prospects.” He added, “We’ll proceed to develop modern applied sciences and applied sciences to fulfill numerous wants.” “We’ll proceed to develop our companies,” he mentioned.
Kim Min-beom, Donga.com reporter [email protected]
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2024-06-05 05:49:21