2024-07-09 08:14:09
A personalized diet with a ‘full body’ x-ray to assess a woman’s body composition and create a nutritional plan for her with the aim of increasing the chances of pregnancy. This is the method tested by the nutrition experts of the Genera team, led by the scientist Gemma Fabozzi, head of the B-Woman center for women’s health, in collaboration with the team of Laura di Renzo, professor of home nutrition -hospital at Tor University Vergata of Rome, who presented the results of their pilot test at the 40th conference of the European Society of Reproductive Medicine and Embryology (Eshre), ongoing in Amsterdam.
“It is known from the data in the literature – explained Fabozzi, the first author of the work – that being overweight, overweight or obese increases the risk of repeated embryo implantation failures or spontaneous abortion, either due to the effect the importance of adipose tissue in reproduction”. But it is not a small question of weight. “The body mass index (Bmi) is the most used index to define anthropometric characteristics, but – under the expert – it represents an inaccurate indication of body composition, with the risk of incorrectly calculating the percentage of fat mass and ignore possible reproductive failure. This study aims to analyze the body composition of obese patients using dual-energy X-ray absorptiometry (Dxa), the gold standard for the assessment and localization of lean mass, regardless of body weight, providing a three-dimensional image of the weights of The physical organs that can be followed are important to develop personalized nutritional programs for patients with incontinence problems”.
The test included 66 women, of which 50 have had children and 16 with a history of repeated implantation failures of embryos made with assisted fertilization. The classification of body composition using Dxa was carried out and it was discovered that “this gene and bone mass differ between pregnant and non-pregnant patients: compared to the previous, non-pregnant women who have succeeded to Pma show differences in the distribution muscles are especially important. in the lower part of the body, and in the dust of the bones”.
“The analysis of the microbiota – continues Fabozzi – also shows great differences between the two groups: the patients with an increased proportion of Proteobacteria and Enterobacteriaceae, which are bacteria that cause problems of internal infections that common which is known to be a risk factor. for the formation of the fetus is greater than 4%, on average, the normal presence of these microorganisms”.
“It is basically – Renzo points out – the determination of body mass, divided into muscle, fat and bone. The condition of infertility is in fact caused by a reduction in the lean mass with the result and an expansion of the size of the fat mass, not only in the visceral , but also peripherally, compared to pregnant women, those with infertility problems have a lower bone mass at the trunk level, which occurs regardless of the patient’s BMI,” he said.
“The goal is to make the way we can evaluate the body composition of a sterile woman more objective – Fabozzi notes – Today we base ourselves on Bia (bioimpedance measurement), BMI and weight, which are indices inaccurate, but still easy to use with Dxa, a type of full body x-ray, we can study how lean and fat there is, how it is distributed, with the image of bone and fat composition which is clearly different between those who are fertile and those who are not fertile Studies must now continue to better understand these differences, identify patients at risk of infertility and develop targeted nutrition and lifestyle care for each “
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