2024-10-01 10:16:51
A study was carried out Mount Sinai Foster Heart Hospital in New Yorkin collaboration with the National Center for Cardiovascular Research (CNIC), has shed light on the atherosclerosisA disease characterized by the accumulation of fatty substances and other substances in the arteries, which can restrict blood flow and increase the risk of cardiovascular disease.
The study, published in ‘Journal of the American Academy of Cardiology(JACC), showed that the burden of silent atherosclerosis and its progression in people without symptoms are independently associated with all-cause mortality.
Despite advances in cardiovascular research, there is little evidence on whether the extent and monitoring of atherosclerosis in asymptomatic individuals, especially in carotid artery disease, can predict overall mortality.
Valentin Fusterthe director of the Mount Sinai Cardiovascular Institute and CNIC, and the coordinator of the study, confirmed that the main goal of the study is to assess the predictive value of silent atherosclerosis in relation to death, beyond cardiovascular risk factors.
The BioImage project, which Fuster also leads, is a pioneer in demonstrating the use of 3D echocardiography and other advanced imaging technologies to detect atherosclerosis in its early stages, before symptoms appear. “The long asymptomatic course of the disease offers an unexplored opportunity,” says Fuster.
The study included 5,716 asymptomatic adults (mean age 69, 56.7% women) who were examined between 2008 and 2009. The participants underwent an arterial ultrasound to measure carotid plaque loads and images were calculated from check blood count.
Ana García Álvarez, co-author and head of Occupational Psychology Hospital Clínic Barcelonaexplained that the carotid plaque, a cholesterol accumulation and other factors, can narrow the carotid arteriesincreasing the risk of serious events such as stroke.
During a follow-up of 12.4 years, 901 deaths (16%) were recorded among the participants.
The findings indicate that both carotid plaque burden and coronary artery disease are associated with total mortality. Furthermore, carotid plaque progression provides additional prognostic information, also linked to mortality.
For CNIC researcher Borja Ibáñez, vascular ultrasound, a non-invasive and inexpensive test, can offer important predictive information that helps stratify patients and distinguish lifestyle recommendations and risk factor management.
Fuster concluded that this study highlights the importance of early detection and screening subclinical atherosclerosiswhich can improve the prediction and prevention of general mortality, which is a valuable tool for medical work.
#fat #arteries #increases #risk #death