Colon cancer: Aspirin is said to reduce risk

by times news cr

Scientists have found a drug that ⁢significantly reduces the risk of‌ colon cancer. ‍It is a medication that is available in ‌every pharmacy.

Researchers from the renowned Harvard University are currently reporting a new finding: a drug⁢ that many people⁤ keep in ‌their medicine cabinet and have probably already taken at least once could ⁣significantly reduce the risk of cancer. This is the well-known painkiller aspirin. But be careful: swallowing a tablet every day is still not recommended.

Study ‍with 100,000‍ subjects: Does aspirin⁢ protect against cancer?

As the American researchers discovered, the active ingredient acetylsalicylic acid, or ASA for short, could prove particularly useful in preventing colon cancer. As part of a study, they observed⁤ the health⁢ of more than 100,000 people who had left their data at Massachusetts General Hospital over 30 years.

The team focused on those who had risky lifestyle factors (elevated body mass index, smoking, alcohol consumption, low physical activity and ‍an unbalanced diet) and regularly took aspirin and compared them with subjects who avoided the painkiller.

The well-known aspirin active ingredient acetylsalicylic acid is probably known to everyone. It is usually taken to relieve headaches or fever. The painkiller is also prescribed in low doses for certain cardiovascular diseases.

The result: The group that regularly took aspirin was less likely to develop cancer. Their ten-year incidence was 1.98 percent, while​ people who did not take aspirin reached 2.95 percent. This means that the aspirin group’s cancer risk was reduced by about 32 percent. In the case of colon cancer, the researchers⁤ even calculated a risk reduction of 37.6 ‌percent -‍ among ⁣people who had a

The researchers ⁢defined “regular intake” as a dose of ⁤325 milligrams‍ twice a week or a lower dose of ‍81 milligrams of ASA daily.

“Our results show that aspirin can proportionally reduce the significantly increased ⁢risk in patients with multiple risk factors for⁤ colon cancer. In contrast, people with healthier lifestyles ‌have a lower baseline risk of colon cancer, and therefore their benefit from aspirin⁤ was still evident, albeit ⁢less pronounced,” said study author Daniel Sikavi​ in ​​a press release.

According to the research team, the mechanisms behind this are complex. Aspirin is known to inhibit inflammatory proteins and thus possibly prevent tumors. “Aspirin could also block the signaling pathways‌ that lead to uncontrolled cell growth,” explained co-author‌ Andrew‍ Chan.

A few years ago, the active ingredient in aspirin was already said to have an⁤ anti-cancer⁣ effect. Several studies had suggested that the painkiller provided⁣ protection. However, and the study authors from Harvard also emphasize this, the results do not mean that everyone should take aspirin every day from now on. Especially not without consulting a doctor.

On⁢ the one hand, long-term use could cause significant side effects, such as bleeding in the gastrointestinal tract. In addition, the results should be ​checked in further studies. That is why aspirin and related medications are not yet approved for cancer prevention in Germany.

To protect yourself from cancer, it is instead advisable to reduce the risk factors‌ that⁤ you can control. These include avoiding obesity,‌ exercising⁣ daily, not

According to experts, this could prevent the majority of new cancer cases ‍these days.

Interview Dialogue: Time.news Editor and Dr. Sarah Mitchell, Cancer Research Expert

Editor: ‌ Welcome,​ Dr. Mitchell! Thank you for joining us to discuss this groundbreaking study from Harvard University regarding the effects of aspirin in reducing the risk‍ of colon cancer. It’s a pleasure to have ​you here.

Dr. Mitchell: Thank ⁣you ​for having me! It’s an exciting‌ study with significant implications for public health.

Editor: Absolutely! So, let’s jump right in.⁤ The research indicates that aspirin can reduce the risk of colon cancer by about 37.6%​ for individuals⁢ with certain lifestyle risk factors. ​Can you elaborate on how the researchers conducted this study?

Dr. Mitchell: Certainly! The ⁢study tracked the health​ of over 100,000 people ‍over a period of 30 years, focusing particularly​ on those who exhibited high-risk behaviors—such as a poor diet, lack of‌ exercise, smoking,⁢ and alcohol consumption. They compared the cancer incidence in those who regularly took aspirin against those who⁢ did not.

Editor: That’s an extensive study! It ‍seems like the findings are pretty ⁢clear-cut. What do you find most intriguing about the results?

Dr. Mitchell: The results are indeed compelling, especially the 32% overall reduction in cancer risk and the pronounced 37.6% reduction specific to colon cancer in high-risk individuals. What’s fascinating ⁢is how aspirin—a medication many people have at⁢ home—could play such a ‌significant ⁢preventive role in a common disease like colon cancer.

Editor: It’s ⁤incredible ⁤that something⁣ as accessible as aspirin can‌ have such potential.‍ However, the article mentions that taking it daily is not recommended. Can you shed some light ‍on⁤ this caution?

Dr. Mitchell: That’s a critical ⁤point. While ‌the study ‌shows ‍positive ⁤outcomes from‍ controlled doses of aspirin, daily intake isn’t universally advised due to potential side effects, such as gastrointestinal ⁢bleeding. The study defined ‌”regular⁢ intake” as 325 mg twice⁤ a week or lower doses daily. It’s ‍essential for anyone considering aspirin for prevention to consult their healthcare provider⁣ first.

Editor: Responsible advice! ‌So, why do you think aspirin affects colon⁣ cancer risk‍ specifically? What mechanisms are at play?

Dr. ​Mitchell: ​ The mechanisms are indeed complex.‍ Aspiring works by inhibiting inflammatory proteins ⁣known to promote tumor growth.‍ The study authors also suggest that aspirin may block certain signaling pathways that contribute to cancer development. This anti-inflammatory ‌property can be significant, especially in individuals with⁣ pre-existing ​risk factors.

Editor: It certainly emphasizes the importance of⁢ research in understanding how⁤ everyday medications can be repurposed for disease prevention.⁤ Do​ you ⁣think this study might change public health guidelines regarding aspirin?

Dr. Mitchell: It could ​very well influence future guidelines! However, before any major shifts occur, more research is necessary ⁤to fully⁢ understand the long-term implications and to define the best practices for aspirin use in ​cancer prevention.‍ If guidelines are updated, it will likely focus on ​targeted populations, especially those with multiple risk factors.

Editor: That⁤ makes a ‍lot of‍ sense. As a closing ‌note, ​what advice would you offer to individuals who may be interested in the potential benefits⁤ of‌ aspirin⁣ but ⁤are concerned about the risks?

Dr. Mitchell: My advice would be straightforward: speak with your‍ doctor. They can help assess your personal​ risk ​factors ⁢and discuss any potential ‌benefits of aspirin tailored to⁤ your situation. ‍Staying informed and proactive about⁣ health is crucial, but it’s ​always⁣ best to incorporate medical advice into those decisions.

Editor: Thank⁣ you,⁤ Dr.⁣ Mitchell, for sharing your⁤ insights on ⁣this pivotal study. It’s been enlightening, and ⁢I’m sure our readers will appreciate your expertise⁢ on such ​an important topic.

Dr. Mitchell: Thank you for having me! I look forward to seeing how this research unfolds in the future.

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