Mice administered ‘WeGobee’ ingredients reduced breast cancer tumor size

by times news cr

Researchers at the University of Kragujevac conducted experiments on 20 laboratory rats.
Researchers ‍said, “Effectiveness ​was seen from ‍the 14th day⁣ of administration… “Possibility of immunotherapy”

On the 16th, at a ⁤pharmacy ‌in Gangnam-gu, Seoul, a pharmacist is sorting out the stock of ⁢obesity treatment ⁣drug ‘Wegobi’. 2024.10.16 News 1

GLP-1RA refers to obesity treatment drugs such‌ as ‘WeGobee’ and ⁤‘Ozempic’ from Danish pharmaceutical company Novo Nordisk, which⁢ have been cited as the ⁢secret⁢ to weight loss ‌by Tesla CEO Elon ‌Musk‍ and famous model Kim Kardashian. The ingredient is semaglutide, which has‍ a similar effect to​ the GLP-1⁢ hormone secreted in the⁣ intestines when you eat food, suppressing appetite by making you feel full​ even if⁤ you eat less food.

On the ⁤18th, ⁢researchers at the University of Kragujevac in Serbia,​ Sladjana Pavlovic, announced that they had confirmed this after ⁢conducting a study ​on‌ 20 laboratory rats aged 8 to ⁤10 weeks.

As a result, the semaglutide treatment group‍ showed a delayed onset of breast cancer compared to the ⁤control group. The researchers ‌explained, “The tumors ⁣in the semaglutide-administered group were ‌consistently smaller than⁢ the control group throughout the experiment,” ‌and “a significant difference was observed 14 days after semaglutide administration.”

There was⁣ also less ⁢evidence of‍ cancer metastasizing to other tissues. ⁣In the‍ control group, metastasis occurred in all 10 ​out of 10‍ experimental⁣ rats, but in the ⁢semaglutide group, only 5 out of 10 mice developed metastasis.

The researchers explained, “Semaglutide has potential as an immunotherapy agent for breast cancer,” adding, “However, additional research is needed to determine whether ⁤the results of research on mice can be applied to humans.”

Meanwhile, the results of this study ‌were published in the‌ November issue of⁣ the international academic journal ‘Biomedicine⁢ & pharmacotherapy’.

(Seoul = News 1)

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How might​ semaglutide’s dual role in ​treating‍ obesity and breast‍ cancer affect future​ medical approaches?

Interview ⁢between Time.news Editor and Dr. Sladjana Pavlovic, Researcher at the University ‌of Kragujevac

Time.news Editor: Welcome, Dr. Pavlovic. ‍Thank you for joining us today to⁤ discuss your ‍groundbreaking research on semaglutide and its effects ⁢on breast cancer.

Dr. Sladjana Pavlovic: Thank you for having me. I’m excited to share​ our findings!

Editor: Let’s ​dive ‌right in. You conducted experiments on laboratory rats, ​and it seems that‌ semaglutide, an ingredient commonly ‍associated with ​obesity treatment drugs like Wegobi ‌and ‌Ozempic, showed some ​promising results. Can you⁣ summarize⁢ what you⁤ discovered?

Dr. Pavlovic: ​Absolutely! ⁢Our research focused on the effects of semaglutide on​ breast⁣ cancer development in laboratory rats. We found that the rats treated with semaglutide had ‌a delayed onset of ⁤tumors compared to ⁢those that ​received no treatment. The tumors in the ⁢semaglutide group⁢ were also⁢ consistently smaller throughout the experiment.

Editor: That’s‍ fascinating! So, what specific results did you observe in terms of tumor size and metastasis?

Dr. Pavlovic: After just 14 days of semaglutide administration, we observed a significant‍ difference in tumor size between the two groups. ⁣Notably, while all rats in⁣ the control group developed metastasis, only half of the⁤ rats treated with semaglutide ​showed signs of cancer spreading to other tissues. This indicates a robust potential for semaglutide not only⁢ in controlling‌ tumor growth but also in⁣ limiting the spread of cancer.

Editor: It sounds like semaglutide could be more ‌than just ⁤an obesity treatment. You mentioned the possibility of its⁣ use‌ as an immunotherapy agent. Can you elaborate on this potential?

Dr. Pavlovic: Certainly. The mechanisms by which​ semaglutide affects cancer progression are still being investigated, but our findings ⁣suggest it‍ may have immunomodulatory effects. The way semaglutide mimics GLP-1, a hormone that regulates appetite, ⁤hints⁣ at a broader ​role in cellular signaling,‍ which could influence immune responses ⁢to tumors.

Editor: That’s⁣ intriguing! Given that semaglutide has gained popularity for ⁤weight loss, how do you think this dual role might impact future treatment options ⁤for⁢ patients dealing ⁣with obesity and breast cancer?

Dr. Pavlovic: If further studies confirm our findings, semaglutide could become⁤ a two-pronged approach⁤ to‍ tackle⁣ obesity while ⁣simultaneously addressing ⁤cancer risk. This could⁢ open up new avenues in‌ personalized medicine, where we can tailor‍ treatments based on patients’ specific needs and health statuses.

Editor: What are the next steps in your research? Are there plans for further studies?

Dr. Pavlovic: Yes, we’re planning ​to expand our research to include​ larger⁤ animal models and eventually clinical trials in humans. We want to understand the ⁢full spectrum of semaglutide’s effects, not just on cancer but also on overall metabolic health.

Editor: It sounds like you’re onto something very exciting. Before we‍ wrap ‍up, is there a particular message you’d like to share with our readers about your work or the research field⁢ in general?

Dr. Pavlovic:⁢ I would emphasize the importance⁣ of open-mindedness in research. ‌As ​we explore ⁢the therapeutic roles of existing ⁣drugs like semaglutide, we can discover innovative solutions that might significantly impact patient care. Collaboration across disciplines is key to advancing our‍ understanding and treatment of diseases ⁣like cancer.

Editor: Thank you, Dr. Pavlovic, ​for sharing‍ your ​insights and the promising findings of your study. We look forward to hearing ⁢more about your work⁣ in the future!

Dr. Pavlovic: Thank you! I ‍appreciate the opportunity to discuss our research.

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