Center for Medical Genomics Facebook post. Be careful of species. “Omicron” hybrid covid BA.2 + BA.1.1 Mutant Leap Different from the original breed “Wuhan” up to 100 positions, different from BA.2 about 30 positions, not found in Thailand. Warning for negligence There is no scientific data to worry about.
There is an urgent report from Belgium. Reported that there has been a concurrent outbreak of omicron subspecies BA.1, BA.1.1, and BA.2 since December 2021, which is likely to be a reason for the detection of continually invasive hybrids since On February 13, 2022 ago
The Medical Genome Center has downloaded 22 samples of the entire genome of a Belgian hybrid strain from the World COVID-19 database “GISAID” for analysis. found that the genetic code is similar to Omicron Species could not be identified or identified with the Pangolin application (Pango v.3.1.20 2022- 02-28), but by in-depth analysis with the Nextclade application.
The Genome Center added that it found that most of the virus in this cluster genome came from. “Omicron” The BA.2 subspecies, but a small percentage, were inherited from the ORF1a (2832-10029) and ORF1b(160464-18163) genes of the subspecies BA.1.1, Omicron, resulting in a BA.2/ hybrid. BA.1.1 recombined linage caused a leap forward mutation because BA.2 was originally
There were 10 different mutations from BA.1 and BA.1 13 different from BA.2 (Figure 3). Unlike BA.2, about 30 locations are probably the strains with the most mutations at the moment (Figure 2), based on calculations from the genetic code and the time of detection. It was found that this BA.2/BA.1.1 recombined linage had a growth advantage or
Epidemic potency is approximately 0.47 times greater than that of BA.2 (47%) (Figure 4). There are no epidemiological data that the BA.2/BA.1.1 recombined linage strain is more contagious. BA.2 how many %?
There is no clinical data whether infected with BA.2/BA.1.1 recombined linage strains are more or less severe than Omicron strains BA.1, BA.1.1, BA.2.
Immune evasion or vaccine inefficiency is unlikely to differ from BA.2 because many mutations were not found on the genome in the “S” gene that controls thorn formation. from scanning in the world’s COVID-19 database “GISAID”, which is now gradually collecting the genetic code for both
Source: Center for Medical Genomics