March 27, 2022 – Dr. Anan Jongkaewwattana, a biotech virologist, National Science and Technology Development Agency (NSTDA) posted a message via his personal Facebook account Anan Jongkaewwattana stated that from the documents of The UK Health Security Agency has named the Delta-Omicron hybrid virus. officially came out Instead of the less-useful name Deltacron being used today. The document mentions three types of virus hybrids: 1. XD, 2. XE, and 3. XF, with X being a cross or inbreeding. How does each form look at the color labeled? Green is the genetic material of the delta species. dark purple is The genetic material of BA.1 and light purple is the genetic material of BA.2.
XD is a hybrid virus caused by delta and BA.1. This viral variant carries the spike gene of BA.1 into the delta core. The viral particles therefore use the omikron spiny protein BA.1 to enter the cell. Instead, it uses other delta elements to multiply the virus in the host cell. The XD virus form is currently invasive in many countries outside the UK, such as France, Denmark and Belgium.
XE is a hybrid of omicron viruses BA.1 and BA.2. The front end is BA.1 and the rear end is derived from BA.2 because proteins on and in the viral particle surface are made up of the inner part. end of heredity Therefore, if we look at the characteristics of the particles of XE, they are not different from BA.2, only that the pathogenesis or proliferation of viruses that rely on genes in the front may be different. Because the protein is derived from BA.1, it is not much different from BA.2. In summary, this form of virus should not be more of a concern than normal BA.2.
XF is a hybrid virus between delta and BA.1, with all structural proteins derived from BA.1 and some proteins decoded from delta segments. Virus particles are no different from typical BA.1, but some properties may differ because the delta-derived portion of the gene may not be the same as BA.1.
Please note that Delta-BA.2 will not be reported. This is because during the BA.2 outbreak, there were already very few Delta viruses. Therefore, hybridization of viruses is difficult to occur, and among the three forms above Personally, I think XD is most likely to come up with a virus with different properties than the existing one. which must be closely monitored
