Virologists from South Korea have found that up to three strains of coronavirus are capable of infecting three strains at once. Omicron infects lung cells about 4.8 times faster than other strains.
On April 15, 65, Dr. Anan Chongkaewwatana, Director of Animal Health and Management Innovation Research Group The National Center for Genetic Engineering and Biotechnology (Biotech), National Science and Technology Development Agency (NSTDA) posted a Facebook page “Anan Jongkaewwattana” published research results from the South Korean COVID-19 research team. indicate that
A South Korean research team has presented a very interesting experimental result. It brings in advanced technology to more clearly answer the question about the infectivity of each strain of SARS-CoV-2 in human lung cells. The researchers isolated human lung air sac cells in a laboratory and induced them to grow into structures called organoids, a state that closely resembles a real organ in the body. rather than using cell cultures that are usually isolated from lung cancer cells and have been cultured for a long time
Enough of the organoid system of the human lungs. The researchers took four strains of the virus isolated from a patient in South Korea with 100% genetic transcription: equal amounts of the original (GR), Alpha, Delta and Omicron strains. Mix them together and let all four strains of the virus infect the organoid lung they create. The research team used the length of time it took for the virus to incubate cells at different times. interesting is It only took him 5 minutes to find out. Viruses can now infect cells.
After incubating the prepared virus with Organoid lung, the research team isolated the infected lung cells into single cells. Using SMART-seq3 technology, the team says it can read the genetic code in each individual cell with enough detail to isolate the viral strain that infects those cells. that Out of nearly 190 cell transcripts, the researchers found that 52 cells (containing 27.2%) were infected by one virus strain, while up to 85 cells (44.5%) were infected by virus 2. Strain and up to 52 cells, or 27.2%, can be infected with 3 strains at the same time. which is very interesting information This is because previous beliefs about the likelihood of a virus infecting more than one host species at the same time were unlikely to occur easily, but the results of this research suggest that it is not difficult either.
Among the cells analyzed for the type of virus that could infect it. The research team found Most of the cells were infected with omikron strains, followed by Alpha and Delta with the original strain. The team found that omichron was able to penetrate the lung cells used in this study significantly (approximately 4.8 times) faster than other strains… but it is unclear how the results of this study will be. This contradicts previous studies that found omikron badly infects lung cells. Must look at the details of the type of cell used. as well as the differences in viruses
The issue that I am particularly interested in is The likelihood that the virus can multiply itself in the same cell with multiple species at the same time. Because that’s the mechanism for creating all X family of hybrid viruses. If it was this easy, strange looking viruses would probably also be born easily.
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