Genome Center reveals an overview of the Covid-19 epidemic. The number of Thai Covid patients has decreased. indicates that there is a high probability that Prepare to fight endemic disease mode soon
Genome Center, Faculty of Medicine Ramathibodi Hospital has posted a message via facebook Revealing an overview of the COVID-19 epidemic The number of coronavirus cases has continued to decline, saying, “The new wave of coronavirus disease 2019, if one does occur, does not always have to be caused by a new variant, but is highly likely to be caused by omics. Ron subspecies (Omicron sub-variant) that occur as well. If you look at the world now (2/5/2522), you will find that the number of new infections and deaths has decreased.
The overall picture of Thailand after Songkran shows that the number of new infections and deaths has also gradually declined due to people’s cooperation in providing full doses of vaccination. plus needle stimulation and the card does not fall especially physical distancing and wearing a mask including self-checking ATK
The subspecies of omicron in Thailand BA.1 has already gone extinct. BA.2 has gradually decreased in numbers. It is highly likely that Thailand can enter the “endemic diseases” that Thai public health can control the outbreak soon
According to randomly decrypted the entire genome of the coronavirus pandemic worldwide, a new variant of the coronavirus has not been identified that differs from the Omicron.
Humans are very bored with covid-19. I want it to become endemic and be able to be eradicated quickly, either with vaccines or antiviral drugs. Just as we have accomplished in the case of the variola virus, poliovirus and measles virus.
But the 2019 coronavirus has developed itself to stay with us forever. The new wave of coronavirus disease 2019, or the sixth wave in the country, may not always be caused by a new variant that is different from the Omikron. Omicron sub-variants have shown us to continually evolve into subspecies.
By mutating only 1-2 locations on the spike/S gene, it increases the human-to-human transmission capacity faster and replaces the original strain. For example, substituents of omikron BA.4 and BA.5 are increasing in number to replace BA.2 in South Africa, or BA.2.12.1 is increasing in number to replace BA. .2 in the United States
But if observed carefully, the severity of the disease did not increase. The number of severe illnesses or deaths did not increase. Most BA.4, BA.5, or BA.2.12.1 cases were asymptomatic or mild as with the original omicron strain. As a result, the World Health Organization continues to classify these mutant viruses as subspecies of Omikron. did not separate the group to rename
World Health Organization The U.S., UK and European Centers for Disease Control are monitoring three subspecies of omikron, BA.4, BA.5, where new infections continue to rise in South Africa, and BA.2.12.1 at the Centers for Disease Control. Significant increase in new infections found on US east coast
The amino acid alteration on the viral spikes of only one location of BA.4 and BA.5 at the “L542R” location could promote epidemics 63-84% over BA.2.
Whereas a single amino acid change on the spine of B.2.12.1 at the L452Q location could result in “BA.2.12.1” being 96% more infectious than “BA.2”.
BA.4 – Whole genome transcription showed a proliferation advantage of approximately 46% compared to other South African species.
BA.5 – Whole genome transcription revealed a proliferation advantage of approximately 60% compared to other South African species.
BA.2.12.1 – Whole genome transcription showed a 72% proliferation advantage compared to other species in the United States.
It is highly likely that three new sub-variant omikrons, BA.4 and BA.5, could cause a new wave of the coronavirus outbreak in South Africa (Fig. 7) BA.2.12.1 may cause a new wave of outbreaks in the United States (Figure 8), and then may spread worldwide without the need for a new variant of the virus. Different from the Omicron emerges.”
