Guinea Worm Disease Eradication: Update – 2024-2025

by Grace Chen

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Guinea Worm Eradication Efforts Show Progress, But Challenges Remain in Africa

Despite meaningful strides in global health, the fight to eradicate dracunculiasis, commonly known as Guinea worm disease, continues in several African nations. Recent data indicates 15 human cases were identified worldwide in 2024,a slight increase from the 14 reported in 2023,but early 2025 numbers suggest a potential downturn. Ongoing surveillance and intervention programs are facing hurdles, particularly related to animal infections and regional instability.

Global Case Numbers and Trends

In 2024, nine human cases of dracunculiasis were reported in Chad and six in South Sudan. This represents a marginal increase from the 14 cases reported across both countries in 2023. However, preliminary data for January-June 2025 reveals only one confirmed human case, compared to three during the same period in 2024, offering a glimmer of hope.

Animal infections, though, present a more complex picture.A total of 664 animal infections were reported in 2024 – a 22% decrease from the 854 reported in 2023. But, the 550 animal infections reported from january-June 2025 represent a 20% increase compared to the 459 reported in the same period in 2024.

Specific Updates

Angola reported no human cases in 2024,but saw a significant 79% increase in dog infections between 2024 (39 cases) and january-June 2025 (70 cases). Genetic analysis indicates Angola’s D. medinensis strains are distinct from those found in other countries. Authorities are implementing dog tethering programs alongside water treatment with temephos.

Cameroon, which was certified Guinea worm-free in 2007, re-emerged as a transmission area in 2019 due to imported cases from Chad. No human cases were reported in 2024 or January-June 2025, but 310 and 398 infected animals were reported, respectively, concentrated near the Chad-Cameroon border. Cameroon is expanding surveillance through trained local volunteers and increasing compliance with its dog tethering policy, reaching 79% in recent efforts.

Chad continues to bear a significant burden, reporting nine human cases in both 2023 and 2024, and one case during both January-June of 2024 and 2025. Animal infections decreased by 43% in 2024 (281 cases) and 44% during January-June 2025 (80 cases) compared to the previous year. Surveillance covers 2,785 villages, and awareness of rewards for reporting cases is high, reaching 62% and 55% of residents surveyed in 2024 and January-June 2025, respectively.

Ethiopia has maintained a zero-case status for human dracunculiasis since January 2023. While two infected baboons were detected in 2024, one did not meet the case definition. Surveillance is active in 474 villages, and awareness of reporting rewards is exceptionally high (96% in 2024, 99% in January-June 2025). Villager-initiated dog and cat tethering programs are also underway.

Mali reported no human cases during January 2024-June 2025, a marked improvement from the single case reported in 2023. Animal infections decreased by 39% in 2024 (28 cases) but saw a slight increase in January-June 2025 (two cases). transmission is intricate by the trade of dogs for consumption,and interventions are hampered by civil unrest in affected areas.

South Sudan reported six human cases in 2024 and two in 2023, with no cases reported during January-June 2025. Animal infections, including those in wild carnivores, were detected in 2024, but none were reported in the first half of 2025. Sporadic civil insecurity continues to challenge surveillance and intervention efforts.

The Importance of Training and Political Commitment

The success of guinea worm eradication efforts relies heavily on well-trained public health personnel. Ongoing training programs focus on case detection, containment

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