Psychedelic Medicine: New Clinical Guidance Released

Millions struggle with mental health conditions that don’t respond too standard treatments. Now, a leading digital resource is adding guidance on a potentially groundbreaking approach: psychedelic medicine.Johns Hopkins Medicine and Unbound Medicine announced a major expansion of the Johns Hopkins Psychiatry POC-IT Guide on 2026/01/31 02:55:39, introducing the first-of-its-kind clinical guidance on using psychedelics in mental healthcare.

A New Frontier in Mental Health Treatment

The updated guide aims to equip clinicians with the knowledge to navigate the rapidly evolving field of psychedelic-assisted therapies.

• Up to 30% of people with major depression don’t respond to conventional therapies.
• Psychedelic-assisted therapies are among the most studied innovations in mental health.
• The Johns Hopkins Center for Psychedelic and Consciousness Research developed the new guidance.
• The updated guide includes patient education materials and aligns with the latest DSM-5-TR criteria.

The new guidance within the Psychiatry Guide provides healthcare professionals with evidence-based recommendations for safe and effective decision-making.It’s designed to improve outcomes for patients facing challenging conditions. The importance of this guidance was emphasized at a recent Johns Hopkins panel, which explored the expanding role of primary care clinicians in managing complex psychiatric conditions.

Experts at the panel stressed the promise of psychedelic therapies,but also highlighted the necessity of thorough patient screening and open interaction between clinicians and patients to ensure safe,evidence-based care.

Beyond the psychedelic content, the update includes patient education materials to improve understanding and bridge the information gap between providers and those they serve. The guide also aligns with the latest DSM-5-TR criteria and features updated drug sections.

“This update marks another milestone in our longstanding collaboration with Johns Hopkins Medicine,” said Bill Detmer,MD,CEO of Unbound Medicine. “For 15 years, the POC-IT Guides-delivered through the Unbound platform-have helped clinicians access essential information, deliver better care, and achieve meaningful improvements in patient outcomes.”

The new psychedelic guidance is now available through the Johns Hopkins Psychiatry Guide app, accessible via the apple^® App Store, google Play^® Store, and through institutional access.