Consuelo Walss-Bass, a biochemist and author, published a memoir exploring her family’s struggle with schizophrenia, blending personal history with scientific research on the disorder’s genetic and environmental roots.
Consuelo Walss-Bass, a biochemist and professor at UTHealth Houston, has spent decades studying schizophrenia’s biological foundations. Her newly released book, ¿Por Qué Mi Hermana? (Why My Sister?), intertwines the story of her mother and sister’s lived experiences with the scientific quest to unravel the disorder’s causes.
A Family’s Silent Battle
Walss-Bass’s mother, Eugenia, was diagnosed with schizophrenia in the 1970s, a time when mental health care was rudimentary. Growing up in Torreón, Mexico, and later in Ohio, Walss-Bass witnessed her mother’s hallucinations and the family’s struggle to cope. Mi madre y mi hermana ya se acostumbraron a oír las voces, pero siguen ahí, she wrote in an interview with El País, describing how her sister, Paty, also experienced the disorder. The book details the family’s isolation, religious coping mechanisms, and the societal stigma surrounding mental illness.
The narrative also reflects on Walss-Bass’s own journey. After her mother’s hospitalization in 1975, she began to see the disorder not just as a personal tragedy but as a scientific puzzle.
Walss-Bass shared, I experienced it first with my mother, then with my sister. At first, the voices are so confusing that they become aggressive. They still hear them, but now they talk to them. They are still there, but calmer.
highlighting the evolution of her family’s relationship with the illness.
Genetic Research and Unanswered Questions
Walss-Bass’s scientific work focuses on identifying genetic markers linked to schizophrenia. Since the early 2000s, her team has contributed to the discovery of 287 genes associated with the disorder.
Walss-Bass explained, But a person doesn’t have 287 mutations; the problem is discovering which combination will occur in each one.

emphasizing the complexity of genetic interactions. Environmental factors, such as early-life stress, also play a role, as seen in twin studies where only one sibling develops the condition.
The book critiques the lack of basic research into mental illnesses.
Walss-Bass noted, No one conducts basic research on mental illnesses.
advocating for deeper exploration of biological mechanisms. She also questioned the medical community’s inability to explain why some family members develop schizophrenia while others do not, a mystery she hopes future generations will solve.
A Literary and Scientific Synthesis
¿Por Qué Mi Hermana? has been described as a hybrid of memoir and science writing, blending emotional storytelling with technical analysis.
Walss-Bass’s writing avoids clinical detachment, instead offering intimate scenes: her mother leaving the house at dawn with a baby, her sister sitting motionless on a bed to avoid wrinkling her uniform, and the toll of psychiatric hospitalizations.
The Broader Implications
The book underscores the gap between scientific understanding and lived reality. Despite advances in genetics, schizophrenia remains poorly understood, with no definitive cure. Walss-Bass’s work highlights the need for interdisciplinary approaches, combining biology, psychology, and social context.
Walss-Bass wrote, Medicine still cannot explain why Paty and not Chelo.

a question that resonates beyond her family, reflecting the broader challenge of mental health research.
For readers, the book offers more than a personal story—it challenges assumptions about heredity, environment, and the limits of medical science. As Walss-Bass puts it,
Walss-Bass stated, The problem is discovering which combination will occur in each one.
a reminder that some mysteries may take generations to unravel.