Information as of July 2, 2022
The BA.5 mutant virus will become the dominant strain found from the patient instead of BA.2 from now on. Because there are doctors, patients, relatives, friends, children, and grandchildren who have been infected in a row. Call and ask to talk a lot. in the past week This organism is characterized by a mutation at the L452R site, replacing highly charged arginine or glutamine in place of the non-charged amino acid leucine at 452, located at the RBD near the spiny protein where it binds to the ACE2 cell receptor of the ACE2 cell receptor. Humans cause the virus to come off and grab onto the surface of human cells more tightly. This localized mutation allows the BA.5 mutant virus to evade neutralizing antibodies caused by vaccination or infection with COVID-. 19 get better as well
However, those vaccinated with the 3rd and 4th booster doses of mRNA vaccination within 5 months still have good immunity to alleviate the severity of BA.5 infection. Topical conditions, such as sore throat, stuffy nose, dry cough or slight mucus The antiviral drugs in the favipiravir, molnupiravir and paxlovid groups are still effective for this BA.5 strain. Staying away from crowded places for more than 30 minutes will be safe from infection or if you are infected, it is force majeure and get a small number of infections, the more the symptoms are mild and stimulate your immune system further. As for anyone who recommends vaccinating against COVID-19 every 4 months, you don’t have to follow it. Wait to see the outbreak of the BA.5 strain before waiting for the new vaccine. Good luck everyone
Article by
Prof. Honorary Dr. Amorn Leelarrasamee
Member of the Medical Council and Vice President, Siam University
Royal College of Physicians of Thailand