“Chickenpox” is an international public health emergency. The same status as “COVID-19”, but in terms of prevention with “vaccination” is “smallpox” or “Monkey pox” is not yet widely needed. May consider only certain groups. Currently, there are 4 models.
“Chickenpox” is an international public health emergency. The same status as “COVID-19”, but in terms of prevention with “vaccination” is “smallpox” or “Monkey pox” is not yet widely needed. May consider only certain groups. Currently, there are 4 models.
Dr. Supakit Sirilak, Director-General of the Department of Medical Sciences, said that at present, there are 3 main forms of smallpox vaccine that the World Health Organization recommends. Rare but severe side effects were found due to the fact that it was a proliferative microorganism in human cells. Therefore, it cannot be given to children, pregnant women, people with impaired immune systems. And people with eczema type skin disease. Then a blister appears within 3-4 days and a pustule scabs in 3 weeks, resulting in scarring.
2. Model 3 Made in the USA a weak pathogen A few side effects were found. Can be given to more people using 2 doses injected under the skin. allowed to protect Smallpox (monkeypox) by the US Food and Drug Administration since 2019. If there is a need for it, it may be this version and the 3.4 version is made from Japan. is a live vaccine Caused by gene editing, it can be used to prevent chickenpox. Use 1 dose by dipping a needle in the vaccine and kicking the upper arm to cause a wound. But there is no permission to prevent smallpox.
In Thailand, there is now a “smallpox vaccine” that can be used to prevent “Small pox” which is produced by the Government Pharmaceutical Organization (GPO) and has been kept well for more than 40 years, amounting to 5 hundred thousand doses and can also be used if necessary. It is the first generation vaccine. Live vaccine is stored in dry powder form at Celsius. Produced from animal saliva The form is applied by dripping into the skin and using a needle to poke the skin with a scratch to allow the vaccine to penetrate.
The Department of Medical Sciences The quality of the human smallpox vaccine was conducted. In this smallpox, 13 smallpox vaccines were found to have good physical characteristics. Appearance is a dry powder that clumps into light yellow lumps. be dissolved with distilled water become clear, light yellow It is acidic – alkaline. In the range of pH 7.38- 7.52 (general standard pH 6.0-8.0), the amount of febrifuge ranged between 4.20- 31.1 EU/ml (general standard, not more than 200 EU/mI).
The uniqueness test revealed that it was a virus in the smallpox virus group. Orthopoxvirus and the vaccine has a potency between 6.42- 6.86 LogTCIDso/ml (World Health Organization standard must be greater than or equal to 5.4 Log TCIDs/ml)
“The smallpox vaccine from the Government Pharmaceutical Organization, 13 generations, still meets the standard of general viral vaccines and is still valuable. If an outbreak occurs in the country and the smallpox vaccine is not available in a global outbreak situation The available smallpox vaccine could be used to prevent chickenpox. However, to be able to use it in an emergency situation will require cooperation from all parties involved in considering the benefits and risks and alternative vaccines available. This is for safety for those who have received the vaccine,” said Dr. Supakit.
while Dr. Opas Karnkawinpong Director-General of the Department of Disease Control (Cor.) discussed the necessity of vaccinating against monkeypox to the general public that This disease is treated symptomatically. It seems scary, but the severity of the disease is not much. There is currently no direct antiviral drug. As for the vaccine currently being produced and prepared to be used by many companies. The Department of Disease Control is in the process of pre-ordering the preliminary vaccine. There are still existing vaccines for chickenpox that the Government Pharmaceutical Organization (GPO) is keeping in the process that may be used, based on indications of efficacy, side effects and a situational assessment for further use.
“Vaccination is looked at as needed. Based on the current situation, there is no need for widespread vaccination. But it may be necessary to inject to specific groups such as laboratory staff. Medical and public health workers who provide close care to patients Since this vaccine has some side effects, the pros and cons may need to be weighed during the injection. and not injecting,” said Dr. Opas.
In line with the joint statement of 5 professional medical organizations, namely Royal College of Physicians of Thailand Royal College of Pediatricians of Thailand Infectious Disease Association of Thailand Pediatric Infectious Disease Association of Thailand and the Association of Preventive Medicine of Thailand Issue a statement of clarification on chickenpox
state one that The smallpox (human smallpox) vaccine will also protect against chickenpox. But since Thailand has stopped vaccinating against smallpox almost 50 years ago, people over 50 years old should be immune to the disease from smallpox vaccination. But those who are younger are not immune. But there is a small chance that this disease will spread to Thailand. Therefore, there is no need for the general public to rush to find this vaccine.