Dr. Theerawat revealed that there was an analysis of information. case of covid patients taking antiviral drugs Come back to be new or rebound, which will be caused by covids. Is it true or not? and this case study I have used both of these drugs, “Monulpiravir” (Molnupiravir) and “Paxlovid” (Paxlovid). Better and how badly will it be? have information to recommend
Prof. Dr. Teerawat Hemajuta, Head of Emerging Disease Health Sciences Center Faculty of Medicine Chulalongkorn Hospital, the Thai Red Cross Society posted an article on the stubborn doctor via Facebook, Thirawat Hemajuta, Thiravat Hemachudha, on August 1, 2022, discussing information on patients infected with COVID-19. and received antiviral medication But it came back again, stating that infected with coronavirus, received antiviral medication come back again don’t panic not all and there is a promotion condition, there is a hotline for the MoPH and the NHSO
reporting from the US by analyzing the data Between January 1, 2022 and June 8, 2022 11,270 were treated with paxlovid or 2,374 were treated with molnupiravir within 5 days of infection.
There are 3 types of rebounds or rebounds:
Characteristics 1. There is a new infection from the examination.
Characteristic 2. There is a recurrence of symptoms. These include fever, chills, cough, shortness of breath, fatigue, muscle aches, headache, sore throat, stuffy nose, runny nose, tastelessness, odor, vomiting, diarrhea, rash.
Characteristic 3. Must be hospitalized new appearance There was no difference in the use of paxlovid or molnupiravir in people with underlying medical conditions. There will be more comebacks.
for paxlovid at 7 days and 30 days
Characteristic 1 found 3.53% and 5.4%
Characteristic 2 Found 2.31% and 5.87%
Characteristic 3 found 0.44% and 0.77%
for molnupiravir at 7 and 30 days
Characteristic 1 Found 5.86% and 8.59 %
Characteristic 2 Found 3.75% and 8.21 %
Characteristic 3 found 0.84% and 1.39%
when looking at the surface Similar to molnuvipavir, there is a greater recurrence.
But when analyzing propensity score matching, which is a method of manipulating variables and factors to ensure reliability. More precisely, in identifying risks, it is found that the risk between The use of these two drugs No difference, but depends on the condition or congenital disease of the infected person, heart disease, high blood pressure, cancer, paresis, lung disease, kidney disease, liver disease, obesity, diabetes, immune system disease, transplantation organ including the administration of immunosuppressive drugs and unrelated with vaccination or not
mechanism cause of comeback “I don’t know for sure.” But may be related to the treatment, the virus cannot be completely eliminated or the virus is drug resistant?
However, antiviral therapy reasonably according to the nature of the symptoms that is more In the Thai people who have already used Fah Talai Thieves does not improve within 2 days, it is necessary to take antiviral drugs to prevent more severe symptoms until you have to go to the hospital
#BackboneMCOT
Reference and thanks for information from:
Facebook : Thirawat Hemachutha Thiravat Hemachudha
https://www.facebook.com/thiravat.h