The Nolotil continues for another year best selling drug in 2022 in Spain. This is revealed by the latest study carried out by the Business Federation of Spanish Pharmacists, which places this analgesic used to treat moderate or intense pain among the most used in our country.
Although its name is that of the commercial brand, the active principle that forms it is the metamizol, as indicated by the Information Center for Authorized Medicines (CIMA) belonging to the Spanish Agency for Medicines and Health Products (Aemps). This medication is commonly used for treat severe painwhether post-operative or post-traumatic, of colic type or of tumor origin, in addition to being used in cases of high fever in which the patient does not respond to other drugs.
However, as with other medications, Nolotil can also produce Adverse effects in patients who consume it, which can range from frequent (affecting 1 in 10 people) to very rare (affecting 1 in 10,000 people).
But what are the side effects What can the consumption of Nolotil produce? How often can they manifest? These are the reactions it can cause according to the CIMA.
Serious skin reactions
One of the most common side effects that the consumption of Nolotil can cause is the appearance of severe skin reactions. Therefore, it is recommended to stop taking metamizole and seek medical attention if any of the following serious side effects occur:
– reddish patches non-raised, circular or target-shaped patches on the chest, often with central blisters, peeling skin, ulcers in the mouth, throat, nose, genitals, and eyes (may be preceded by fever and flu-like symptoms)
– generalized erythemaelevated body temperature and enlarged lymph nodes (DRESS syndrome or drug hypersensitivity syndrome)
severe symptoms
Other adverse effects that can cause concern when taking Nolotil can be the appearance of a sick feelingaccompanied by nausea or vomiting.
Besides, the feverthe feeling tired o Symptoms such as loss of appetite, dark urine, light-colored stools, or yellowing of the skin or eyes, among others, may also be indicative of “Hepatic injury”according to the AEMPS.
Mild allergic reactions
The appearance of mild allergic reactions They can also be some of the more common side effects that metamizole can cause. Among these, there may be skin reactions and mucous membranes such as itching, burning, redness, swelling; difficulty breathing; gastrointestinal discomfort that can lead to generalized hives, swelling of the feet, hands, lips, throat and airways; severe bronchospasmand even heart rhythm disturbances and decreased blood pressure.
Frequency of side effects of Nolotil
The most common side effect (may affect 1 in 10 people) is hypotension (Decreased blood pressure). For their part, the rashes and skin reactions They can also be very common, affecting 1 in 100 people who consume Nolotil.
Rare side effects of Nolotil, which may affect 1 in 1,000 people, include “allergic reactions which usually occur during or just after administration, but also hours later, skin rashes and hives, decreased number of white blood cells (leukopenia) and asthma.
Thus, among the rarest reactions, which affect 1 in 10,000 people, are the skin reactions in which vesicles or blisters appear (toxic epidermal necrolysis, Stevens-Johnson syndrome), kidney problems with decreased or suppressed urine output, increased amount of protein excreted in the urine, or inflammation of the kidney (interstitial nephritis) . In addition, there may be a severe decrease in white blood cells (agranulocytosis) which, in some cases, can lead to death; while the decrease in the number of platelets in the blood (thrombocytopenia) can cause inflammatory lesions in the mucous membranes, sore throat and fever.