Long aftermath in children and young adults with myocarditis and pericarditis after mRNA vaccination

by time news

Myocarditis and pericarditis are known side effects of the mRNA corona vaccines, which occur much more often in boys and young men after vaccination than after infection. In addition, a high percentage (3.5%) of them had subclinical (not yet detectable) cardiac damage detected after the second vaccination. Until now it was unknown how long patients suffered from symptoms with adequate treatment.

A study of 228 children and young adults (12-29 years) in the leading journal Lancet Child and Adolescent Health (1) now indicates that at least 90 days after diagnosis, the vast majority of patients still have one or more abnormal features or findings. reported.

Of 33 patients considered unrecovered according to patient and caregiver data, 97.0% (32/33) reported after a minimum of 90 days [figuur i, er is maar 1 patiƫnt met alleen blauwe vlakken] one or more abnormalities: shortness of breath, chest pain, daily medication, decreased physical activity, increased heart damage markers in the blood (Troponin), an abnormal echo or electrocardiogram and/or abnormal MRI. From the 195 [alle kolommen in ii] patients considered recovered according to patient and caregiver data reported 83.6% (163/195) after a minimum of 90 days [Slechts 32 kolommen hebben geen rode vlakken] one or more of these problems.

Cardiac biomarker, imaging and functional status at individual patient level at least 90 days after diagnosis, according to recovery status of myocarditis. Each column represents a patient, and each row represents a diagnostic test, cardiac imaging, or the patient’s functional status. Symptoms are self-reported by the patient. The class (i or ii) was derived from linked patient and caregiver data and included 33 patients who did not recover, and 195 patients who were considered likely or fully recovered. From ref (1), Figure S2, colors adjusted for clearer display.

These data indicate a long aftermath of heart damage after corona mRNA vaccines, while long-term effects are still completely unknown, which should be a point of attention especially for children and young adults. All the more so because 38.8% (69/178) of patients considered to have recovered had elevated heart damage markers [Troponine rij: 69 rood, 178 rood of blauw, 17 wit]. At 5.6% (10/178) [10 rood, 178 rood of blauw, 17 wit] an abnormal echocardiogram. At 16.1% (24/149) [24 rood, 149 rood of blauw, 46 wit] an abnormal electrocardiogram and in 55.9% (52/93) [52 rood, 41 blauw, 93 rood of blauw] an abnormal heart MRI. More than 90 days after diagnosis.

Incidentally, Denmark and Sweden have stopped offering mRNA corona vaccines to healthy young people or persons under 50 years of age.

References:

  1. Kracalik I, Oster ME, Broder KR, Cortese MM, Glover M, Shields K, Creech CB, Romanson B, Novosad S, Soslow J, Walter EB, Marquez P, Dendy JM, Woo J, Valderrama AL, Ramirez-Cardenas A, Assefa A, Campbell MJ, Su JR, Magill SS, Shay DK, Shimabukuro TT, Basavaraju SV; Myocarditis Outcomes After mRNA COVID-19 Vaccination Investigators and the CDC COVID-19 Response Team. Outcomes at least 90 days since onset of myocarditis after mRNA COVID-19 vaccination in adolescents and young adults in the USA: a follow-up surveillance study. Lancet Child Adolesc Health. 2022 Sep 21:S2352-4642(22)00244-9. doi: 10.1016/S2352-4642(22)00244-9. Epub ahead of print. PMID: 36152650.

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