A medical journal reveals a rare case of a 19-year-old Chinese man suffering from Alzheimer’s disease. The world’s first young without knowing the cause and not related to heredity
Foreign news agencies reported The case for the discovery of a new medical patient Alzheimer’s disease (AD) is no longer just a disease that primarily affects the elderly. Because in China, the world’s first 19-year-old Alzheimer’s patient was found.
Dr. Jia Jianping, MD, a specialist in neurology at the Innovation Center for Neurological Disorders Xuanwu Hospital Affiliated with Beijing Capital Medical University, China reported Alzheimer’s disease patients who were only 19-year-old teenagers.
In the medical journal Journal of Alzheimer’s Disease, an article in a 19-year-old teen prone to Alzheimer’s disease revealed a 19-year-old man with gradual memory impairment over two years onset of the disorder. memory at age 17, and results of the World Health Organization-University of California, Los Angeles (WHO-UCLA AVLT) verbal learning test also showed memory impairment.
According to reports, patients began to have trouble concentrating and learning. His team first looked at the boys’ two cognitive assessments (memory, attention, language ability, math ability, spatial awareness, etc.), where the MMSE and MoCA test scores were. normal
A year later, the patient had severe short-term memory loss. inability to recall events from previous days or to store personal belongings As well as being difficult to read and slow to respond to, from October 2020 to October 2021, his MoCA score dropped and lost 3 points in his memory. Subsequently, the patient still had gradual dementia. even trying to remember what he had eaten As a result, the patient had to drop out of school halfway.
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Positron tomography–magnetic resonance imaging with 18F fluorodeoxyglucose reveals bilateral hippocampal atrophy. Mild atrophy and metabolic syndrome were found in bilateral temporal lobes. Examination of the patients’ cerebrospinal fluid revealed an increased p-tau181 protein concentration and a decreased amyloid-β 42/40 ratio.
From whole genome sequencing (WGS), no gene mutations and infections were found, such as Apo E, APP, PSEN1 and PSEN2, and there was no family history of Alzheimer’s disease. and no other cause that cause memory loss, such as genetic problems, infections, or other diseases
Histology is currently lacking and the patient is too young to receive a brain biopsy. Because a brain biopsy is invasive Therefore, Dr. Jia Jianping calls attention to the possibility of Alzheimer’s disease in young people.
The world’s first Alzheimer’s disease patient in 1906, it is widely believed that This disease mostly occurs in the elderly. It is caused by chronic neurological degeneration that begins slowly and gradually loses perception, memory, and ability to read and speak. Subsequently, there was an increase in mental disorders over time. eventually leading to the inability to take care of themselves
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