2023-10-25 21:12:07
Neutralizing antibodies would be able to bring patients into remission, without the need for lifelong antiretroviral treatment. The first clinical trials will begin at the end of 2023 in France.
A future where we could be cured of AIDS: the idea seems utopian. However, forty years after the discovery of HIV-1, the virus responsible for AIDS, new perspectives in the fight against this infection have just emerged thanks to the discovery of a treatment which, unlike existing ones, would not have no need to be taken for life. Teams from the Pasteur Institute, Inserm and AP-HP, with the support of the National Agency for Research on AIDS and Viral Hepatitis (ANRS), highlighted the involvement of specific antibodies in virus control. Pending a clinical trial which should be launched in France at the end of 2023, this discovery nourishes the hope of a lasting remission of the infection without treatment. The results appeared in the journal Cell Host & Microbe.
Among HIV-1 patients, there are rare people treated at the early stage of infection and able to control the virus after stopping their antiretroviral treatment…
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#candidate #treatment #lasting #remission