2024-07-29 12:16:40
The fight for HIV treatment It goes back decades. It is one of the goals of the scientific and medical community. Therefore alone six people in the world have managed to heal illness thanks to cell transplantation. Now, we report information that we can have seventh person to be cured of HIV.
The UNAIDS report was presented at a press conference earlier International AIDS Conference in Munich. This is a man who can be cured thanks to a stem cell transplant that he received as part of the treatment for cancer that he has been suffering from.
This man was diagnosed with HIV in 2009 and in 2015 he underwent a stem cell transplant as part of treatment against a AML, according to ‘National Geographic’. In 2018 he stopped antiretroviral treatment and, almost six years later, he continues to maintain an undetectable viral load.
From the report, the scientists explained that a unique characteristic is that the stem cell donor only has one copy of the mutation that gives resistance to CD4 against HIV, instead of two copies, as happened in other documented cases of healing. If the success of this intervention is confirmed, it could mean an increase in the reserve of donors of this type, which gives more patients the opportunity to receive HIV treatment. seropositive with cancer.
Stem cell transplantation is a risk intervention that occurs in life or death cases due to the presence of cancer. However, this provides information of great value in terms of progress toward achievement cure for HIV.
Timothy Brown, called the ‘Berlin patient’, was the first case of all. He received two bone marrow transplants to treat acute myeloid leukemia in 2006. The donor’s cells had two identical copies of a mutation called CCR5-delta32. This change causes CD4 cells to not display the CCR5 receptor on their surface, which is what many strains of HIV use to enter cells.
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