Advancements in Lung Cancer Treatment: Chemotherapy, EGFR-targeted Therapy, and Immunotherapy as Primary Strategies

by time news

2023-06-20 10:48:41

Chemotherapy, EGFR-targeted therapy, and immunotherapy are the pillars of lung cancer treatment. By overcoming the blood-brain barrier with second-generation EGFR-directed tyrosine kinase inhibitors, patients with brain metastases can be better cared for.

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Better patient selection is needed for the use of immunotherapy and adjuvant EGFR-targeted therapy prolongs patient survival. These are important findings presented at this year’s ASCO Annual Meeting in Chicago.

Approximately one third of patients with non-small cell lung cancer (NSCLC) present with resectable disease. Adjuvant therapy with osimertinib, an EGFR tyrosine kinase inhibitor (EGFR TKI), demonstrated clinical benefit over placebo in the phase III ADAURA study. Overall survival (OS) results were presented at ASCO.1

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