2024-06-21 03:28:47
(ANSA) – ROME, JUNE 20 – Intracerebral transplantation of mind stem cells may open up new remedy prospects for Amyotrophic Lateral Sclerosis (ALS) and A number of Sclerosis (MS), blocking cell dying processes and normalizing the physiopathological image of the sufferers by means of the discharge of trophic substances – i.e. produced by the physique and able to guaranteeing the survival of cells and in addition stimulating their development – and anti inflammatory substances. This emerges from the outcomes of the Part 1 scientific trial for secondary progressive MS and the current begin of the Part 2 trial for ALS, offered at the moment on the headquarters of the Pontifical Academy for Life by the Translational Drugs group of professors Angelo Vescovi and Letizia Mazzini .
Within the experimentation for the remedy of MS, a neurodegenerative pathology characterised by an anomalous motion of the immune system, the analysis group led by Vescovi – scientific director of the Irccs Casa Sollievo della Sofferenza Opera di San Pio da Pietralcina, president of the nationwide Bioethics committee and founding father of Revert Onlus – has accomplished a part 1 scientific trial with human mind stem cells, and can now proceed with part 2 geared toward consolidating the outcomes on the security of the remedy, evaluating the dosage and the potential therapeutic efficacy of the cells. As regards analysis for the remedy of ALS, nevertheless, the recruitment of sufferers for the part 2 scientific trial with the identical cells started in January 2024. Below the course of Mazzini, of the ALS Skilled Heart of the Novara College Hospital, between March and Might 2024 the hospital group transplanted two sufferers, and the third operation will happen in July. This objective was achieved due to the encouraging outcomes obtained with part 1 of the trial, which started in 2012. The trial carried out by Vescovi’s analysis group is the one one on the earth to have reached part 2. The price of this new experimental part is 4.3 million euros. Funding of 1 million euros was acquired due to a European Pnrr name (the mission ranked first out of 300 submitted). Remedy with mind stem cells represents, to this point, the 2 specialists say, one of many doubtlessly only therapies towards these pathologies. (HANDLE).
2024-06-21 03:28:47