Alzheimer’s illness: an epidemic of scientific misconduct

by time news

2024-06-12 16:00:07

The scientific literature on Alzheimer’s illness continues to be revised, and the standard of the related research is questioned. In December 2023, as a result of“inconsistency” in sure numbers and biostatistical errors, Creation thus refutes a research led by neurobiologist Marc Tessier-Lavigne. It was printed in 2009, when he was the president of the Californian firm Genentech, and offered by its first creator as “Change Standing” within the understanding of neurodegenerative illnesses.

In the meantime, the Canadian researcher took the place as president of the well-known Stanford College (California). He needed to resign in the summertime of 2023, after an inside investigation revealed that many fraudulent investigations had been carried out within the laboratories he led. It is your coaching Creation has been cited greater than eight hundred instances within the scientific literature.

This very respectable rating, nevertheless, doesn’t evaluate to the two,343 citations from one other research, printed in 2006 Creation, which confirms the position of the buildup of β-amyloid proteins within the etiology of Alzheimer’s illness. The lead creator, Karen Ashe (College of Minnesota, Minneapolis), simply talked about PubPeer – a web site that means that you can query, anonymously, the standard of scientific work – that you’ve got determined to ask to your resignation. He determined to take action two years after an investigation by the newspaper Datathe candidate Creation, reveals many suspicious photographs. These manipulations had been found by an American neurobiologist Matthew Schrag, and confirmed by psychologist Elisabeth Bik, an professional in scientific fraud detection.

Learn additionally: This text is reserved for our subscribers Alzheimer’s illness analysis: suspicions of scientific misconduct

Matthew Schrag discovered these information just a little by likelihood, when he was commissioned by small buyers from the pharmaceutical firm Cassava Sciences who feared that simufilam, his anti-Alzheimer’s drug, had been developed on the idea of fraudulent research. On this mission unbiased of his work on the Vanderbilt College Medical Heart, Matthew Schrag has compiled a file of thirty-four articles from researchers linked to the promotion of Cassava Science “Vital considerations of scientific misconduct”.

The neurobiologist has additionally seen a 2006 research led by Karen Ashe, the primary signature of which was a French researcher who studied in Caen, Sylvain Lesné, who joined his laboratory as a postdoctoral fellow. Matthew Schrag has additionally discovered problematic areas across the battle of science fiction by the French.

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