An advance for science: they discover the possible origin of Parkinson’s in water bacteria

by time news

2023-05-09 20:57:00

He Parkinson It is a progressive disorder that affects the nervous system, that is, the symptoms worsen over time. Although it is believed that the signs obey a loss of neurons or environmental factors, a recent study suggests that a bacteria could be involved in the development of this disease.

The Parkinson’s disease It has doubled in the last 25 years. According to information from the World Health Organization (WHO), around 8.5 million people live with this disorder, which has claimed the lives of 329 thousand people in the last 20 years.

What happens to a person with Parkinson’s?

A person with Parkinson’s produces motor and non-motor symptoms by affecting their nervous system. In accordance with Mayo Clinic Medical Institute specialistsyou may develop tremors in the hands, arms, legs, jaw, and face, muscle stiffness, slowness of movement, or balance problems, in mild cases.

Scientists discover possible origin of Parkinson’s disease in bacteria/ Photo: iStock

The Parkinson’s disease It occurs when nerve cells in a part of the brain, called the substantia nigra, become damaged or die. These cells produce a substance called dopamineresponsible for the transmission of messages between the nerve cells and essential for movement control and coordination.

What is the relationship between bacteria and Parkinson’s?

A recent study published in the scientific journal Frontiers in Cellular and Infection Microbiologyconducted by a team of scientists from the University of Helsinki and the University of Eastern Finland, suggests that a bacteria of the genus Desulfovibrio, present in the water, could be one of the causes of the Parkinson.

To reach this conclusion, the scientists analyzed the feces of 10 Parkinson’s patientsfinding in common bacteria of the genus Desulfovibrio. Once identified, these bacteria were fed to a group of Caenorhabditis elegans worms (genetically modified) to verify the existence of the human α-synucleic protein as it was associated with Parkinson’s.

Scientists discover possible origin of Parkinson’s disease in bacteria/ Photo: iStock

Why is the human α-synucleic protein important?

This protein is important in the release of neurotransmitters, substances that send essential signals so that nerve signals can be transmitted through neurons, hence the importance that the worms that were used as models could synthesize this protein.

When the worms were fed the bacteria Desulfovibrioextracted from the Parkinson’s patients, was observed in his brain cells an increase in human α-synucleic acid. Although there is a huge difference between humans and worms, the truth is that C. elegans share many genes and molecular pathways with us, one of the reasons why they were chosen to carry out the study and their relevance.

Although it is said that the intestine is our second brain, the truth is that the neurons that it possesses are smaller and with a simpler structural form than those found in the brain. Yes, the intestine secretes serotonin as a neurotransmitter for nerve cells to facilitate the passage of food through the intestine, but it is far from a second brain.

Scientists discover possible origin of Parkinson’s disease in bacteria/ Photo: iStock

What is, is that there may be a link between the microbiota intestinal with the development of some neurological diseases because some bacteria that live in the intestine could influence the brain Health, As suggested by the recent study on the Parkinson.

Although more studies should be carried out on the relationship of bacteria Desulfovibrios with Parkinson’s, without a doubt, it is a great revelation in the fight against this neurodegenerative disease.

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If you are interested in learning more about Parkinson’s, stay and watch the following video.

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