AstraZeneca vaccine, it is also possible for people over 60 to have heterologous vaccination in case they have had serious adverse reactions affecting the coagulation sphere with the first dose of the anti Covid vaccine Vaxzevria. This is what the Italian Medicines Agency Aifa indicates in responding to requests received from some Regions regarding the interventions to be taken following the appearance of a serious adverse reaction after the first AstraZeneca dose in this age group.
Aifa, having obtained the opinion of its Technical-Scientific Commission (Cts), states that “it is not possible to provide general recommendations in the face of the heterogeneity of the cases that require specific clinical evaluation. However, similarly to what has already been decided for subjects under the age of 60 “for whom the mix was given the green light,” applying the principle of maximum precaution, the Agency specifies that, in subjects who have experienced serious adverse reactions of the thrombotic type or in any case affecting the coagulation sphere after the administration of Vaxzevria, it is possible to proceed with the booster with an mRna vaccine “, informs Aifa.
For the other series of adverse reactions, on the other hand, “it is believed that, in the absence of data deriving from ad hoc studies, it is not possible to express general recommendations that disregard the examination of specific” reactions “and the clinical evaluation of individual cases” .