2023-06-13 15:03:58
Bacteria helps with acid formation
In life-threatening septicemia, an abundance of this bacteria in the biofilm in the mouth has been observed when the infection is at its peak.
S. sputigena apparently interacts efficiently with S. mutans, helping this bacterium produce acid, which attacks enamel and dentin.
Trapped by glucans
S. mutans is particularly good at producing glucans, which have an enhancing effect on dental plaque formation. S. sputigena, which can move across surfaces, is captured by the glucans.
When this happens, S. sputigena multiplies and forms cell-based, honeycomb shaped (octagonal) ‘superstructures’, which encapsulate and protect S. mutans.
Together they make caries worse
Together, these two bacteria form an aggressive couple that stimulates the formation of acid, which causes tooth decay to spread.
The researchers’ discovery provides a completely new insight into the development of caries and may help to target the prevention of this condition in the future.
In addition, the research has revealed new and unknown mechanisms underlying the development of bacterial microfilm (biofilm), which may be relevant in other clinical contexts.
#insight #origin #cavities #teeth