Benefits of early treatment with anticoagulants for stroke due to atrial fibrillation

Benefits of early treatment with anticoagulants for stroke due to atrial fibrillation

2023-05-30 01:27:20

An international study led in Israel by Prof. Natan Bornstein, director of the Brain Unit at the Shaare Zedek Medical Center in Jerusalem, states: Early treatment with anticoagulants in the case of a stroke, as a result of atrial fibrillation, has been proven to be effective and safe and even to reduce the chances of a repeat stroke.

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The EALN study, which was conducted among approximately 2,013 patients from all over the world and in Israel, and which was coordinated in Israel by Prof. Bornstein, presents new results regarding the correct time of treatment with anticoagulants in the case of stroke in people with atrial fibrillation. Its results were published this week inNEJM.

In the study, people who had a stroke as a result of fibrillation and cerebral embolism were examined. The centers in the world that were involved in the research determined according to imaging whether the infarction was mild, moderate or severe, and the patients were rerandomized. Some of them received the treatment that was customary until today according to the guidelines, and some received the treatment early depending on the size of the infarct. The results of the study showed that the early treatment did not cause excessive bleeding and even reduced the risk of a recurrence.

Atrial fibrillation is a heart rhythm disorder that is common in about 5% of the population over the age of 65 in the world and is responsible for 20% of stroke cases caused by blockage of blood vessels in the brain by a clot. The fibrillation can cause the formation of a clot that is carried to the brain and causes a stroke.

Until now, the usual treatment in these cases was the administration of anticoagulants. Fearing that the anticoagulants would cause bleeding, it was decided that in the case of a small or transient cerebral infarction, the treatment would be given after a day; If it is moderate, give it after six days and if it is large, wait about two weeks before giving the anticoagulants. This way of treatment was determined without established studies.

Prof. Bornstein: “The research brings exciting and innovative news in the field of stroke treatment. A stroke caused by atrial fibrillation in the heart is a relatively common phenomenon in the population, and until now it was treated in a certain way that was not based on research but was determined by experts in the field. Following the results of the current study that I led and that was carried out In several centers, it will be possible for patients who have experienced a stroke as a result of atrial fibrillation to receive faster and safer treatment and to prevent a repeat stroke. This, on the basis of comprehensive, controlled and thorough scientific research.”

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