Better understanding the genetics of obesity, a priority for care

by time news

2023-09-10 18:54:18

Monogenic obesity is classically distinguished from polygenic obesity. Peakstock – stock.adobe.com

DECRYPTION – This issue is all the more important in the current context, with the arrival of new pharmacological treatments for obesity.

In France, almost one in two adults are now overweight, and 17% are obese. This prevalence can even exceed 20% in economically disadvantaged populations. These worrying figures have continued to increase for forty years. This is a major public health problem, obesity being a chronic disease associated with numerous complications, in particular type 2 diabetes, cardiovascular diseases and at least thirteen forms of cancer.

Obesity is a complex disease, involving genetic susceptibility in interaction with multiple environmental factors, including changes in eating habits, level of physical activity, psychosocial context, stress or even sleep and disruption of biological rhythms. .

In recent years, a whole section of research has been devoted to the study of the genetic and biological mechanisms of obesity, and much progress has been made. Understanding the genetic aspects…

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