The rebellion against knowledge carries serious consequences. From 2000 to 2017, vaccination against measles has managed to reduce deaths caused by this virus by 80%. However, in the absence of vaccination, infection with the measles virus is highly likely. 90% of unvaccinated people will be infected by the virus if they come into contact with another infected person. These are the reasons why the anti-vaccine movement has achieved that this disease has undergone a global rebound of 300%, thus affecting more than seven million children and directly killing more than one hundred thousand, each year.
One hundred thousand direct annual deaths, and additional indirect deaths. Measles, a disease that lacks specific treatment, causes immunosuppression, that is, it leaves the body’s defenses very weak and thus allows the attack of other infectious microorganisms that can cause serious illnesses and even death, such as intestinal infections that cause very severe diarrhea. difficult to control, and pneumonia.
Now, an international group of European and American researchers are studying the effects of measles on the immune system with the most modern tools available. Thus, using the VirScan assay, a technique that allows the identification of all antibodies in the blood against pathogenic microorganisms, they study 77 unvaccinated children in the Netherlands before and after a natural measles infection. The results of this study indicated that measles caused a decrease in the repertoire of protective antibodies against other microorganisms, ranging from 11% of this repertoire in the most fortunate children to 73% of the repertoire in the most affected ones. The children’s immune system seemed to have forgotten that in the past it had fought against many microorganisms. This phenomenon has been termed immunologic amnesia.
The researchers are also studying whether this decrease in the repertoire of protective antibodies occurred in the same way in children vaccinated against measles. This was not what happened. Although the vaccine was effective in protecting against measles virus infection to a similar extent to that achieved by natural infection with this virus, the vaccine did not cause any immunosuppression and left the children’s defenses perfectly prepared for fight other infections.
These new revelations indicate that vaccination against the measles virus not only protects against this disease, but also helps to maintain the efficacy of other vaccines and generates a better state of defenses to face the many threats of infectious diseases that lurk. to the lives of children.
Michael J. Mina et al. (2019) Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens Science 1 NOVEMBER 2019 • VOL 366 ISSUE 6465, pp 599.
Jorge Laborda, December 15, 2019.
Outreach works by Jorge Laborda
Kilo of Science Volume I. Jorge Laborda
Kilo of Science Volume II. Jorge Laborda
Kilo of Science Volume III. Jorge Laborda
Kilo of Science Volume IV. Jorge Laborda
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Kilo of Science Volume X. Jorge Laborda
Kilo of Science Volume XI. Jorge Laborda
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