The major obstacle encountered by researchers in developing an effective vaccine against HIV is the strong tendency of the virus to mutate. yes – stock.adobe.com
DECRYPTION – The development of an AIDS vaccine has kept researchers in suspense for forty years.
It is truly the Grail, the one that many scientists are determined to conquer. Forty years that the international scientific community has devoted itself to the development of a vaccine against HIV, without conclusive success at this stage. Despite immense therapeutic progress, which allows most patients with access to treatment to live properly, and prevention methods that are diversifying, the epidemic is still going on. In France, 5,000 new cases were discovered in 2021; worldwide, 1.5 million. The preventive vaccine remains a crucial public health issue, and every promising avenue is scrutinized.
After the disappointment, last week, at the end of the last phase 3 trial in progress in the world (Mosaico trial promoted by the Janssen laboratory), the preliminary phase 1 results of the team of Frenchman Yves Lévy (Vaccine Research Institute, ANRS-Upec) awaken legitimate hope, although it is still too early to comment on their future…
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