Single Exercise Session Shown to Slow Cancer Cell Growth by Up to 30%
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New research reveals even a single bout of physical activity can considerably impact cancer progression in survivors, reinforcing exercise as a vital component of oncological care.
A groundbreaking study has revealed that just one session of exercise – whether resistance training or high-intensity intervals – can reduce the growth of cancer cells by as much as 30% in breast cancer survivors. the findings, originating from Edith Cowan University in Australia, underscore the critical role of physical activity not just in overall health, but as an active and possibly therapeutic part of cancer treatment.
The Immediate Impact of Exercise on Cancer Cells
the research focused on the immediate biological effects of exercise in women who had previously overcome breast cancer. Researchers discovered that a single training session triggers an increase in the production of mioquinas, proteins released by muscles possessing anti-cancer properties. These molecules, circulating in the bloodstream, were shown to slow the growth of cancer cells by 20 to 30% in laboratory tests. Importantly, this effect was observed wiht both strength-based exercises and high-intensity interval routines, suggesting a broad range of physical activities can elicit similar beneficial responses.
How Mioquinas Combat Cancer
Mioquinas play a central role in this process. Generated during muscle contraction, these proteins contribute to tissue repair and growth, stimulate the formation of mitochondria, blood vessels, and neurons, and regulate the immune system and metabolism. In the context of cancer, mioquinas act as messengers that can inhibit the proliferation of tumor cells and bolster the body’s natural defenses.
To arrive at these conclusions, a team led by Francesco Bettoriga recruited 32 breast cancer survivors, randomly assigning them to either a resistance training or high-intensity interval session. Blood samples were collected before, promptly after, and 30 minutes post-exercise. Analysis revealed important increases – ranging from 9% to 47% – in levels of decorin, Interleukin 6 (IL-6), and SPARC. Furthermore, the reduction in growth of MDA-MDA-231 cancer cells reached up to 29% following the exercise session.
Kerry Couneya, a professor at the University of Alberta and co-director of the trial, stated that exercise is “no longer only an intervention to improve the quality of life, but a cancer treatment of colon that should be available for all patients.” The study’s randomized and controlled design provides a high level of evidence, leading specialists to agree that physical activity should be systematically integrated into oncological care.
The CHALLENGE trial’s exercise program included walking, cycling, and other aerobic activities tailored to each participant’s abilities, with guidance from kinesiologists or physiotherapists.In the United Kingdom, Charles Swanton, clinical head of the Cancer Institute, pointed out the notable benefits exercise offers patients, even without the use of drugs. Christopher Booth, from Queen’s University in Canada, added that an exercise program with a personal coach can reduce the risk of recurring or new cancer, improve well-being, and increase longevity.
Mioquinas: A Multifaceted Impact on Health
The function of mioquinas and their impact on health extend beyond tumor control. Released during exercise, these proteins stimulate the creation of new blood cells and vessels, regulate metabolism, and contribute to tissue repair. They also help maintain muscle mass,a critical aspect of recovery and relapse prevention in oncological patients.
Despite the robust evidence, implementing exercise programs within cancer care faces challenges. Many oncological centers lack the infrastructure and specialized personnel to integrate these interventions effectively.Experts emphasize that, similar to chemotherapy, a system must be established to facilitate access to and adherence to physical activity, adapting programs to each patient’s individual needs and abilities.
Specialists currently recommend three to four weekly sessions of moderate physical activity, such as 45- to 60-minute walks, cycling, or swimming.Personalization and professional guidance are key to sustained adherence and maximizing benefits.
The researchers’ conclusion is unequivocal: weight loss without exercise is insufficient for those seeking to reduce cancer recurrence risk. Only regular physical activity preserves and develops muscle mass, stimulates mioquina production, and solidifies exercise as an indispensable ally in both cancer prevention and treatment.
