Professor Jinyoung-joo Jin, Department of Gastroenterology, Inha University Hospital, presented research
A study showed that chronic hepatitis B patients with liver stiffness of 11 kPa or more have a 3.33 times higher risk of developing liver cancer than patients without liver stiffness.
According to Inha University Hospital on the 23rd, Professor Youngjoo Jin of the Department of Gastroenterology recently announced important research results in predicting the risk of developing hepatitis B virus and hepatocellular cancer.
This study is a meta-analysis that measured liver stiffness in patients with chronic hepatitis B using instantaneous elastography and systematically analyzed the risk of developing liver cancer.
Meta-analysis research refers to a method of collecting the results of individual studies and reanalyzing them statistically.
The research results were recently published in the international journal Clinical and Molecular Hepatology, and the journal is recognized as having high influence in the related field.
Chronic hepatitis B is one of the main causes of liver cirrhosis and liver cancer.
Previously, liver biopsy was used as a standard to diagnose cirrhosis, but this had the limitation of being an invasive procedure and difficult to use clinically.
In contrast, the liver fibrosis scan test used in this study is attracting attention as a useful tool for early detection of cirrhosis and predicting the risk of liver cancer by non-invasively measuring liver stiffness.
Professor Jinyoung-Joo Jin’s research team analyzed related papers published from 2010 to 2023 and found that patients with chronic hepatitis B who have liver stiffness of 11 kPa or more as measured by liver fibrosis scan test have a 3.33 times higher risk of developing liver cancer compared to patients without the disease. derived.
In particular, the sensitivity for predicting the occurrence of liver cancer based on stiffness above 11 kPa was 61% and the specificity was 78%, increasing the accuracy of diagnosis.
This study suggests a method to more precisely predict the risk of developing liver cancer in patients with chronic hepatitis B, and is expected to be of great help in early detection and establishing appropriate prevention strategies.
Professor Jin said, “Patients with high liver stiffness have a high risk of developing liver cancer, so more thorough surveillance and management are needed for them.”
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