‘Fulminating Mpox’ threatens AIDS patients, warn researchers – News

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A very serious form of Mpox, a disease formerly known as monkeypox, has been detected in AIDS patients, according to a study published on Tuesday (21).

“A severe, necrotizing form of mpoxide (could) become an AIDS-defining illness,” write the authors of this Lancet study.

Smallpox, which spread across the world in 2022 before slowing its spread, primarily affected men who had relationships with men.

In this population there is a greater proportion of people infected with HIV, a virus that in its most advanced stage triggers AIDS, which affects the patient’s immunity and makes him vulnerable to other diseases.

The researchers were interested in the particular risks posed by mpoxide in patients already infected with HIV and looked at nearly 400 people who were infected with HIV and mpoxide.

They identified a very severe form of the disease, which they described as “fulminating pox”.

This manifestation, concentrated in patients with advanced HIV infection, causes massive necrosis of the skin, genitals and lungs.

Of the patients examined, 27 died. All of them exceeded the generally accepted limit for talking about AIDS: less than 200 CD4 T lymphocytes per mm3 of blood.

These deaths represent a large part of the hundreds of deaths recorded in the context of the mpox epidemic, among several tens of thousands of cases.

For the researchers, these conclusions should lead health authorities to seek, as a priority, to vaccinate people affected by HIV against Mpox.

They asked to add this severe form of Mpox to the list of diseases characteristic of AIDS.

The list includes about fifteen pathologies considered specifically dangerous in case of advanced HIV infection.

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