2023-11-20 17:23:15
Women with Heart Failure-Related Cardiogenic Shock Have Worse Outcomes Than Men
A new analysis of registry data has shown that women who experience cardiogenic shock due to acute heart failure have worse outcomes and more vascular complications than men. The study, which was presented at the American Heart Association (AHA) Scientific Sessions in Philadelphia, is considered one of the largest contemporary analyzes of real-world registry data on the characteristics and outcomes of women and men with cardiogenic shock.
According to senior author Dr. Navin Kapur from Tufts Medical Center in Boston, USA, the study highlights the need to identify barriers in diagnosis, management, and technological innovation for women with cardiogenic shock in order to improve outcomes. Dr. Kapur and his team founded the Cardiogenic Shock Working Group in 2017 to collect high-quality data on cardiogenic shock and found that their patients were dying without enough data about how best to treat them. This prompted the creation of the registry and the detailed data on nearly 9,000 patients with cardiogenic shock from 45 hospitals in the United States, Mexico, Australia, and Japan.
The analysis of the registry data revealed that women with heart failure-related cardiogenic shock had more severe cardiogenic shock, worse survival at discharge, and more vascular complications than men. This was in contrast to the results of cardiogenic shock following a myocardial infarction, which were largely comparable in women and men.
The study also found that differences in BMI and body surface area between women and men may play a role in deciding treatment for cardiogenic shock. Women were generally less likely to receive invasive therapies such as pulmonary artery catheterizations, temporary mechanical support, and cardiac replacement devices.
Dr. Kapur emphasized the need for better solutions or technologies that can be used more effectively on women, as well as the importance of monitoring for vascular complications in women. The results of the study raise awareness about the gender-related disparities in the care and outcome of cardiogenic shock and highlight the need for individualized care to meet the physiological needs of patients. The study’s findings were published in JACC: Heart Failure.
In an editorial accompanying the publication of the study, experts emphasized the need for more research and gender-specific, objective criteria for therapy control to address the gender-related disparities in the care of patients with cardiogenic shock. The study sheds light on the need for better solutions and technologies to improve outcomes and reduce complications in women with cardiogenic shock.
The study highlights the need for gender-specific approaches to the diagnosis, management, and treatment of cardiogenic shock in order to eliminate disparities and improve outcomes for women. More research and data on this issue are needed, and it is crucial to include women in randomized trials to ensure that they are properly represented in the development of treatment strategies for cardiogenic shock.]
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