NK cell (Natural Killer cell) or killer cell It is a type of white blood cell. Important for the innate immunity (Innate immunity) is responsible for monitoring. Identify and destroy abnormal or viral cells. because if these cells are not eliminated May develop into tumors, cancer cells, causing the body to get sick.
In normal humans, there are approximately 5-15% of NK cells. Lymphocytes are found in the bone marrow, liver, uterus, spleen, lungs, as well as the thymus gland and lymph tissue. Lymphatic tissue, like other types of white blood cells, NK cells are produced from stem cells in the bone marrow. They differ from T lymphocyte (T-cells) and B lymphocyte (B-cells) cells in that Inside the cell are large granular lymphocytes.
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Special abilities of NK cells
NK cells are able to find and destroy foreign cells without waiting for stimulation by antigens like other types of white blood cells. making it able to destroy foreign objects such as viruses or abnormal cells like cancer cells immediately They can also produce cytokines to induce other white blood cells in the immune system to respond to foreign bodies.
How NK cells work
In order for an NK cell to destroy a target cell (Target cell), it must first bind between the NK cell and the target cell. They rely on receptors on the surface of NK cells, namely activating receptors and inhibitory receptors. Activating receptor NK cell will destroy that cell. But sometimes the normal cells of the body have transmitters that are close to the abnormal cells. therefore relying on MHC class I proteins on normal cell surfaces. It binds to inhibitory receptors, preventing NK cells from damaging the body’s good cells. This is a mechanism that NK cells use to identify normal cells. out of abnormal cells
The importance of NK cells
The role of NK cells is important in fighting cancer cells. The destruction of NK cells (cytolytic activity) was associated with the incidence of cancer. If this process is reduced Will increase the risk of cancer. In addition, NK cells play a role in inhibiting the spread of cancer (metastasis), for example. Activating receptors NKp30 and NKG2D in cancerous lymph nodes. The more work The higher the diffusion level, the lower it is.
Therefore, taking care of your health for NK cells to work efficiently. Therefore, it is important to keep the body healthy. Ready to fight foreign substances, viruses and abnormal cells such as cancer cells. which started by modifying one’s own lifestyle Turn to take care of health in all dimensions, refrain from smoking, increase exercise. eat nutritious food get enough sleep And take care of your mental state not to stress, just like this, our NK cells will be strong. along with other immune systems of the body that are strong at the same time
BDMS Wellness Clinic Committed to developing and researching health issues to give as a gift of health to all Thai people because of good health Is the best gift Live longer, Healthier and Happier
For more information, please contact BDMS Wellness Clinic Line : @bdmswellnessclinic or https://lin.ee/rdIDv1A Website : www.bdmswellness.com
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