HMB, the common bodybuilding supplement that could help prevent Alzheimer’s

by time news

2023-08-06 09:48:16

Updated Sunday, August 6, 2023 – 09:48

A Rush University Medical Center study reveals that the secret to protecting memory may lie in a muscle-building supplement used by bodybuilders to improve their performance

Bodybuilders participate in a bodybuilding competition. ANTONIO HEREDIAN Neurologist A 19-year-old boy is diagnosed with the earliest case of Alzheimer’s ever recorded Stories The latest performance by Carme Elias: “Alzheimer’s is like a little mouse that every day takes a little of your brain”

The secret to protecting memory may lie in a staple of a bodybuilder’s diet. Researchers at Rush University Medical Center (United States) have shown that a muscle building supplement called beta-hydroxy-beta-methylbutiratoalso called HMBmay help protect memory, reduce plaques, and ultimately help prevent the progression of Alzheimer’s disease. Alzheimer.

HMB is not a prescription drug or steroid, but an over-the-counter supplement available at sports and fitness stores. Bodybuilders commonly use HMB to increase muscle size and strength induced by exercise, while improving your performance. HMB is considered safe even after prolonged use, with no known side effects.

“This may be one of the safest and simplest approaches to stop the progression of the disease and protect the memory of Alzheimer’s patients,” explained Kalipada Pahan, one of those responsible for this research, which has been published in the journal Scientific Cell Reports.

Studies in mice with Alzheimer’s disease have shown that HMB successfully reduces plaques and increases neural growth factors to protect learning and memory.

Previous studies indicate that a family of proteins known as neurotrophic factors it is dramatically decreased in the brains of people with Alzheimer’s and has been found to help the survival and function of neurons, which are cells that receive and send messages from the body to the brain and vice versa.

This new study has shown that, after oral consumption, HMB penetrates the brain to increase these beneficial proteins, restore neural connections and improve memory and learning in mice with Alzheimer-like pathology, as plaques and tangles.

The results of the study indicate that HMB stimulates a nuclear hormone receptor in the brain called PPARa that regulates fatty acid transport, which is key to the success of HMB as a neuroprotective supplement.

“If the results obtained in mice with HMB are reproduced in Alzheimer’s patients, a promising path to treatment of this devastating neurodegenerative disease will be opened,” Pahan detailed.

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