IL-11 protein, key to delay aging

by time news

2024-07-17 15:00:50

Our protinflamory protein in mice can be the ‘Rosette stone’ of age. A study published in ‘Nature‘shows that this enzyme inhibits the health of old mice and increases their life expectancy. The Effects of Il11 Exposure in the present population, although basic clinical trials are underway to understand the effects of this treatment in patients.

The expansion of the area of ​​population is a a colossal challenge Health, social economy laws and economists next year.

Now, the discovery of the group Universidad Duke-Nus Medical School (Singapore) seems to have found the key to delay aging.

The group shows in the previous models of the Interleukin-11 protein (IL11) Effects of aging and controls anti-IL11 treatment Anti-IL11 health care is not the harmful effects of the past, but increases life expectancy.

In previous studies, it has been found that with age, the body increases the levels of protein of the liver and fiber promotes fatty water and energy, two conditions that are characteristics of human age.

According to the researchers, these results are the first in the world to demonstrate that IL11 is a major factor in the past.

After determining the effect of Il11 in the old days, the team showed that by using the same anti-IL11 treatment, the production was activated, going from creating fatty tissue to beneficial fatty tissue. Them brown fat It breaks down blood fats and lipids to help maintain body temperature and burn calories.

According to the researchers, these results are the first in the world to demonstrate that IL11 is a major factor in the past.

The authors investigated how interfering with Il11 activity affects diseases that have genetics and lifestyle. Deletion of the IL11-associated gene has been shown to protect against metabolic decline, diseases, and aging in old age, and extends the lifespan of both sexes by 24.9% in total. Ding il11 with a personal aspect of the production process and muscle functionWhile reducing signs of aging and Hartty in both male and female rats.

In one-week mice (human average of 55 years), inhibition of IL11 increased life and 25.4% in men and 25% in women. IL11 inhibition also appears to reduce the incidence of age-related cancerwhat you have already suggested.

The researchers also observed better muscle function and improved general health in their study, as well as an increase in life expectancy of up to 25% in both varieties.

Unlike other drugs that are known to inhibit specific pathways in the sampling systems including the main sampling methods of cardiovascular diseases Strength and Flailty, Leri Olososisa Isorija.

In addition to these external changes, anti-IL11 treatment also reduces the rate of cell proliferation and maintains the health of the mitochondria and their ability to generate energy.

Teacher Stuart Cooksenior author and professor of the foundation of toxicologyOur goal is that one day, Anti-IL11 therapy will be used in as many people as possible».

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