2024-07-26 05:49:57
The innovative technique will allow conventional antibodies to be revived to fight bacterial infections.
Superbacteria observed from a microscope.
Bacterial infections have once again become a major threat due to the rampant spread of antibiotic-resistant bacteria. Fighting these infections is one of humanity’s greatest challenges. Surgical procedures, from the simplest to the most complex, including organ transplants, chemotherapy and even minor surgeries, are currently high-risk interventions without effective antibiotics to combat them. The development of medical technology is not necessary if the highest risk factor after the operation is contracting an untreated infection.
Finding new effective antibiotics is a challenge for the pharmaceutical industry, because research can last decades without acceptable results, which discourages the investment of resources. “We have the most dangerous bacteria and the worst weapon to fight them,” emphasizes Daniel López Serrano, from the National Center for Science (CNB-CSIC), director of a project that develops innovative strategies to inactivate the antibiotic resistance of superbugs.
In their cellular microbiology laboratory, they are developing a battery of materials that destroy the FMM membrane microdomains and thus cause many of the protein machines responsible for conferring resistance to antibiotics to stop working, causing bacteria The disease does not have an antibiotic to become active and can be eliminated with antibiotics. “We tested the combination of our MMF inhibitor materials with antibiotics to eliminate resistant infections,” he added. With this technique, infections are eliminated, while traditional antibiotics, which are not used due to the emergence of resistance, “In this way we manage to renew the weapon we have to fight infections,” the researcher concluded. M. Baldomà
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