Liverpool host Atletico Madrid at Anfield for an 8pm BST kickoff on Wednesday, September 9, 2026, launching their Champions League campaign under manager Andoni Iraola. The Merseysiders enter the fixture with no fresh injury concerns, though long-term absentees including Hugo Ekitike and Conor Bradley remain sidelined.
European nights return to Merseyside this week as Liverpool step onto the Anfield turf to get their Champions League campaign up and running.
Rotational Pressures and Squad Depth Ahead of European Return
Iraola has hinted that he will look to rotate his squad following Friday night’s victory against Ipswich Town at Portman Road, as he implements his forward press and quick transition style. That puts Frimpong in line for a recall at Anfield after being dropped for the Portman Road trip.
Analysis of the tactical setup reveals a delicate balancing act for the management team. While supporters are eager to see marquee arrivals feature heavily, the demands of balancing domestic rhythm with a demanding Champions League schedule require calculated changes across the pitch. Bringing in fresh legs like Frimpong allows Liverpool to maintain the high-intensity press that Iraola demands without burning out key personnel.
Defensive Adjustments and Personnel Decisions
This potential shift comes as Jeremy Jacquet is not quite fit enough to see out full matches. The French youngster was substituted in Liverpool’s first two Premier League games and limped over the finish line during the weekend fixture against Ipswich.
Meanwhile, the defensive treatment room remains a familiar source of frustration. Wataru Endo has been left out of Liverpool’s Champions League squad list entirely, limiting midfield contingencies.
Midfield Scramble and Attacking Configurations
Trey Nyoni is also pushing for a starting berth after impressing from the bench in recent outings.

Further forward, Alexander Isak is expected to spearhead the attack after being rested just after the hour mark against Ipswich. The Swedish international had earlier bagged a brace for the first time in Liverpool colours, providing a timely boost for the Reds’ frontline. Florian Wirtz is set to continue his role operating in the pocket, looking to establish himself as the key man under the new manager.
The Wide Dilemma and Squad Integration
Questions remain over how Iraola will configure his wide options.

Gakpo has started the season in strong style, contributing one goal and three assists, while Victor Munoz might be rested following his late heroics against Nottingham Forest and subsequent run of matches. Balancing these attacking assets while integrating talent like Barcola will define Liverpool’s tactical evolution through the autumn.
Predicted Lineup and Unresolved Questions
In midfield, Dominik Szoboszlai and Ryan Gravenberch are projected to anchor the center, with Florian Wirtz ahead of them. The predicted front three comprises Rio Ngumoha, Cody Gakpo, and Alexander Isak.
Whether this exact configuration takes the pitch against Atletico Madrid—and how effectively a heavily rotated side can execute Iraola’s pressing system against elite European opposition—remains the central question as Anfield prepares for kickoff.
