cancer It is one of the diseases that has been studied for a long time in medical research. for the discovery of mankind’s way of salvation No matter how far it is, I will reach it If there is a good drug to treatdiseaseI’ve been waiting, but that good drug may not have to go far If found only in “Backyard Garden”
Asst. Prof. Dr. Wongwarut Boonyanukomol, Chairperson of the Bachelor of Science Program Medical Sciences Project to establish Amnat Charoen Campus, Mahidol University Reveal the results of the research which has been published in international medical journals. “Medicine” It was found that essential oils extracted fromVegetable garden “Basil” and “sweet basil” It inhibits the growth of gastric cancer cells at the in vitro level (In vitro).
According to medical microbiology knowledge, Helicobacter pylori (H. pylori) is one of the causes of gastritis. stomach ulcerorduodenum (Peptic Ulcer Disease), includingstomach cancer (Gastric Cancer), which is considered a cancer that is quite dangerous. and has a very poor prognosis.
The research team triedExtracting essential oils from vegetable gardensCommonly found such as basil, sweet basil and thyme were found to inhibit the growth of gastric cancer cells in the laboratory, respectively. This is a research project funded by the Department of Thai Traditional and Alternative Medicine. Ministry of Health
This research project has been co-operated by professors and researchers from many sectors, including a professor in analytical chemistry (Dr. Pornphan Prapatpong) from the Bachelor of Public Health program. Project to establish Amnat Charoen Campus, Mahidol University by Using GC-MS (Gas Chromatography – Mass Spectrometry) apparatus to analyze the key constituents in basil and basil essential oils.
In addition, there was a collaboration from a professor in proteomics (Assoc. Prof. Dr. Orapak Riamthong) from the Faculty of Tropical Medicine, Mahidol University, who helped study and experiment on the expression of proteins in cancer cells. stomach By using the LC-MS/MS (Liquid Chromatography – Tandem Mass Spectrometry) instrument to analyze the molecular mechanisms of essential oils.in inhibiting the growth of gastric cancer cells at the in vitro level And most importantly, this research project has also received cooperation fromRepublic of Korea Research Team (College of Medicine, Gyeongsang National University), which is a long-standing research partner.
In addition to the discovery of biological activity from the three types of vegetable gardens mentioned above. The researcher has conducted an experimental study on essential oils from other Thai medicinal plants such as Plai (Zingiber cassumunar Roxb), which has been conducted in vitro research to test the antibacterial activity of plai essential oil. Acinetobacter baumannii (A. baumannii), Extensively Drug Resistant / XDR strains
It was found that essential oil from Plai showed antibacterial activity against this group of bacteria. and interesting isPlai essential oil exhibits synergistic properties with antibiotics at the in vitro level. by this research It has also been published in an international research journal (Journal of Infection and Public Health).
From the research mentioned above, it is a study at the laboratory or in vitro level. This is considered as important basic information for further study in the future. for researching important substances in medicine to further widespread medical use