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Engaged in regenerative medicine and tissue engineering, reports this morning that it has for the first time been able to produce induced pluripotent stem cells (iPSCs) from human peripheral blood cells.
In this context, the company produced the pluripotent stem cells in a process called reprogramming, after which the pluripotent stem cells exhibited characteristic features of division and differentiation as expected. Pluripotent stem cells have the ability to differentiate into different cells, including nerve cells, thus creating, in combination with the hydrogel (which the company is developing), an autologous neurological implant designed to treat spinal cord injuries in the paralyzed.
Matrisalf develops autologous (self) implants for the regeneration of damaged tissue by using a cellular component and an extracellular component from the patient himself. Implant preparation is done with technology that combines a company-unique hydrogel, sensitive to temperature and produced in a unique process that includes processing of a piece of omentum (intra-abdominal adipose tissue) taken from the patient himself and pluripotent stem cells that are also produced from adult patients.
Dr. Assaf Tucker, CEO of the company: “Our success in human stem cell production is a tremendous achievement for the development team both scientifically and commercially. Establishing independent cell production capability, independent of external subcontractors, will position the company as a key player in cellular therapy and regenerative medicine and save future production costs. We expect “The success in the independent production of cells will be a huge economic opportunity in a market of billions of dollars a year in the field of spinal cord injuries and in the future also in other diseases.”
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